Tania Mutchie Seminar Abstract The Ritter Reaction is a chemical reaction that yields N-alkyl amides from the nucleophilic addition of a nitrile to a carbocation source in the presence of concentrated sulfuric acid. Although it is a simple method for... Read More

Abstract The building block of life, single cells, now have another techniques available for their investigation and quantification of resident compounds through the advent of mass spectrometry. Advances in miniaturization of fluidic systems and pairing of separation methods allow for... Read More

Abstract Human Immunodeficiency Virus (HIV) is a retrovirus that targets the CD4 receptor (CD4R) of T-lymphocytes. Once infected, T cells are compromised and will be unable to mediate the immune response. The depletion of T cells increases the chance of... Read More

Abstract Single stranded DNA (ssDNA) binding proteins (SSBs) bind selectively to ssDNA with high affinity and little sequence specificity, preventing ssDNA from annealing to its complementary sequence. Previously, Ha Lab showed E. coli SSB, a representative homotetrameric SSB, moving on... Read More

Abstract The structure analysis of large biomolecules such as proteins and peptides by mass spectrometry (MS) is very challenging. However, recently introduced MS techniques facilitate this process by controlled fragmentation. Often physiological modifications take place at the amino acid side... Read More

Abstract.  Despite decades of research regarding best practices for the teaching and learning chemistry, as well as two sets of national reform documents for science education, classroom instruction in high school chemistry classroom remains mostly unchanged. One key reason for... Read More