The Chemistry and Biochemistry Department maintains a wide variety of instrumentation but also has access to instrumentation at other UW facilities as well as in industry.
| Manufacturer | Model | Description | Research Group |
| Beckman Instruments Inc. | Optima Ultra-centrifuge L70 | Ultra-centrifuge | Department |
| Bruker | DRX300 | NMR Spectrometer | Department |
| Bruker | DRX500 | NMR Spectrometer | Department |
| Shimadzu | GCMS-QP2010 Ultra | Mass Spectrometer | Department |
| Shimadzu | ICP-MS | Mass Spectrometer | Department |
| Shimadzu | IRTracer-100 | FTIR Spectrophotometer | Department |
| Shimadzu | LCMS-2020 | Mass Spectrometer | Department |
| Shimadzu | LCMS-8040 | Mass Spectrometer | Department |
| Shimadzu | LCMS-IT-TOF | Mass Spectrometer | Department |
| Shimadzu | MALDI-7090 | Mass Spectrometer | Department |
| Shimadzu | UV-2600 | UV-Vis Spectrophotometer | Department |
| Sorvall | RC-6 Plus | Centrifuge | Department |
| Steris | Century | Sterilizer (Autoclave) | Department |
| Steris | Century Amsico Lab 250 | Sterilizer (Autoclave) | Department |
| BioRad | BioLogic LP System | Low Pressure Chromatography System | Frick |
| BMG | FLUOstar Omega | Multimode Reader | Frick |
| Cary | 50 UV/VIS | Spectrophotometer | Frick |
| Cary | Eclipse | Fluorescence Spectrophotometer | Frick |
| Eppendorf | epMotion | Automated Liquid Handling System | Frick |
| EVOS | FL | Cell Imaging System | Frick |
| FluorChem | FC2 | Imaging System | Frick |
| GE | AKTApurifier | UPC 10 | Frick |
| Invertoskop (Axiovert) | 40C Zeiss | Microscope | Frick |
| Mastercycler | ep Realplex | Quantitative Realtime PCR System | Frick |
| TA Instruments | NanoDSC | Differential Scanning Calorimeter | Frick |
| TA Instruments | NanoITC | Isothermal Titration Caloimetry | Frick |
| Thermo Electron Corporation | Varioskan | Multimode Reader | Frick |
| Braun | OP7 | Inert Atmosphere Glove Box | Pacheco |
| Carry | 5000 | Spectrophotometer | Pacheco |
| Jasco | V570 | Spectrophotometer | Pacheco |
| Innovative Technology Inc. | SRS-400-4 | Atmosphere Glovebox | Pacheco |
| Online Instrument Systems | RSM 1000 | Spectrophotometer | Pacheco |
| Opotek Inc. | Brilliant | Optical Parametric Laser | Pacheco |
| Varian | UV/VIS | Spectrophotometer | Pacheco |
| Jasco | J-715 CD | Spectrometer | Schwabacher |