Year of Graduation: 2014
Research Lab: Professor Alexander Arnold
Major Area of Focus: Organic Chemistry

Thesis: The Development of VDR-coactivator Inhibitors and Their Evaluation Using Biochemical and Cell-based Assays

Publications

1. Kelly A. Teske, Ganesha Rai, Premchendar Nandhikonda, Preetpal Sidhu, Belaynesh D. Feleke, Anton Simeonov, Adam Yasgar, Ajit Jadhav, David J. Maloney, and Leggy A. Arnold “A parallel chemistry approach to identify novel nuclear receptor ligands based on the GW0742 scaffold” ACS Combinatorial Chemistry 2017, 19, 646-656.
2. Preetpal S. Sidhu, Kelly A. Teske, Belaynesh Feleke, Nina Y. Yuan, Margaret L. Guthrie, Grant B. Fernstrum, Nishita D. Vyas, Lanlan Han, Joshua Preston, Jonathan W. Bogart, Nicholas R. Silvaggi, James M. Cook, Rakesh K. Singh, Daniel D. Bikle, Leggy A. Arnold “Anticancer Activity of VDR-Coregulator Inhibitor PS121912” Cancer Chemotherapy and Pharmacology 2014, 74(4), 787-798.
3. Kelly A. Teske, Premchendar Nandhikonda, Jonathan W. Bogart, Belaynesh Feleke, Preetpal Sidhu, Nina Y. Yuan, Joshua Preston, Robin Goy, Rakesh K. Singh, Daniel D. Bikle, James M. Cook, Leggy A. Arnold “Identification of VDR antagonists among nuclear receptor ligands using virtual screening” Nuclear Receptor Research 2014, 1, 1-8.
4. Preetpal S. Sidhu, Nicholas Nassif, Megan M. McCallum, Kelly A. Teske, Belaynesh Feleke, Nina Y. Yuan, Premchendar Nandhikonda, James M. Cook, Rakesh K. Singh, Daniel D. Bikle, Leggy A. Arnold “Vitamin D Receptor-Coactivator Binding Inhibitors” ACS Medicinal Chemistry Letters 2014, 5(2), 199-204.
5. Kelly A. Teske, Premchendar Nandhikonda, Jonathan W. Bogart, Belaynesh Feleke, Preetpal Sidhu, Nina Y. Yuan, Joshua Preston, Robin Goy, Leggy A. Arnold “Modulation of Transcription mediated by the Vitamin D Receptor and the Peroxisome Proliferator-Activated Receptor δ in the presence of GW0742 analogs” Journal of Biomolecular Research and Therapeutics 2014, 3, e111.
6. Premchendar Nandhikonda, Adam Yasgar, Athena M. Baranowski, Preetpal S. Sidhu, Megan M. McCallum, Alan J. Pawlak, Kelly A. Teske, Belaynesh Feleke, Nina Y. Yuan, Chinedum Kevin, Daniel D. Bikle, Steven D. Ayers, Paul Webb, Ganesha Rai, Anton Simeonov, Ajit Jadhav, David Maloney, Leggy A. Arnold “PPARδ agonist GW0742 interacts weakly with multiple nuclear receptors including the vitamin D receptor” Biochemistry 2013, 52, 4193-4203.