Chemistry & Biochemistry Colloquium – Christian Hoydic – No-transporting proteins from blood sucking insects

Chemistry Room 180 3210 N. Cramer Street, Milwaukee, WI, United States

Nitrophorins are nitric oxide transporting proteins utilized by the blood sucking insect Rhodnius prolixus. What's unique about these proteins, is they work in tandem with histamines to not only mask their feeding, but also utilize the unique biological characteristic that... Read More

Chemistry & Biochemistry Colloquium – Acid Ceramidase Inhibitors: A De Novo Drug Target and a New Class of Drug for Glioblastoma – Shama Mirza – Hosted by Peter Geissinger

Chemistry Room 180 3210 N. Cramer Street, Milwaukee, WI, United States

Acid Ceramidase Inhibitors: A De Novo Drug Target and a New Class of Drug for Glioblastoma Glioblastoma remains the most common malignant cancer of the central nervous system with an overall survival <1.5 years. Therapeutically resistant glioblastoma or glioblastoma stem-like... Read More

Chemistry & Biochemistry Colloquium – “Determining the impact of protein-protein interactions on Transglutaminase 2 activity” – Tonya Zeczycki from East Carolina University

Chemistry Room 180 3210 N. Cramer Street, Milwaukee, WI, United States

“Determining the impact of protein-protein interactions on Transglutaminase 2 activity” Tonya N. Zeczycki, PhD Assistant Professor Department of Biochemistry and Molecular Biology and the East Carolina Diabetes and Obesity Institute East Carolina Heart Institute Host: Nicholas R. Silvaggi ABSTRACT In... Read More

Chemistry & Biochemistry Colloquium – Balaraman Kalyanaraman from Medical College of Wisconsin – Discovery of new drugs inhibiting NOX isoforms and cancer cell mitochondrial metabolism and bioenergetics

Chemistry Room 180 3210 N. Cramer Street, Milwaukee, WI, United States

NADPH oxidase (Nox) isoforms are a family of enzymes that generate superoxide and hydrogen peroxide as primary oxidants during the activation of oxygen. Nox isoforms play a key role in immunity, infection, and inflammation. Yet, to date there are no... Read More