Acid Ceramidase Inhibitors: A De Novo Drug Target and a New Class of Drug for Glioblastoma Glioblastoma remains the most common malignant cancer of the central nervous system with an overall survival <1.5 years. Therapeutically resistant glioblastoma or glioblastoma stem-like... Read More

Photocatalysis is the process where the rate of a photoreaction is altered by the presence of a substance that is not itself consumed in the reaction. Photocatalysis can be heterogeneous or homogeneous, with the majority of the research up-to-date focused... Read More

“Determining the impact of protein-protein interactions on Transglutaminase 2 activity” Tonya N. Zeczycki, PhD Assistant Professor Department of Biochemistry and Molecular Biology and the East Carolina Diabetes and Obesity Institute East Carolina Heart Institute Host: Nicholas R. Silvaggi ABSTRACT In... Read More

NADPH oxidase (Nox) isoforms are a family of enzymes that generate superoxide and hydrogen peroxide as primary oxidants during the activation of oxygen. Nox isoforms play a key role in immunity, infection, and inflammation. Yet, to date there are no... Read More

Abstract: Diffuse large B-cell lymphomas (DLBCLs) are life-threatening cancers that are the most common form of non-Hodgkin’s lymphomas. The current standard treatment of DLBCL involves the RCHOP regimen. However many patients treated with those therapies relapse. The transcriptional repressor BCL6... Read More

Walk-in Advising and Declare Your Major Day Interested in more information about the Chemistry/Biochemistry program? Majoring in Chemistry or Biochemistry Minoring in Chemistry or Biochemistry Internships Undergraduate research Undergraduate program plans Specific course information Would you like to change from an... Read More

Methylation is a ubiquitous process in all branches of life. Whether it is to regulate the expression of certain genes, or to give stability to the tertiary structure of large biomolecules, all organisms, from the tiniest microbe to the giants... Read More