Cell and Molecular Biology encompasses study of the structure and function of organisms and biological processes at the level of cells, and the macromolecules that define them (DNA, RNA, proteins, lipids, and carbohydrates). Researchers in the CMB Group span many disciplines including Cancer Biology, Neurobiology, and Developmental Biology. Specific areas of research include:
- Regulation of the cytoskeleton in cell and tissue shaping during brain development and disease.
- Cell signaling in cancer development and progression.
- Molecular genetic mechanisms of cell differentiation during plant reproduction.
- Genetic mechanisms underlying neurodevelopmental disorders
- Gene regulatory mechanisms governing development and regeneration of wiring in the nervous system.
Our research employs many model systems including Arabidopsis, C. elegans, zebrafish, mice and mammalian cell culture. Experimental approaches utilize advanced light and electron microscopy, CRISPR-mediated gene editing, genetic screening, genomic analyses, and proteomic analyses.
Cell & Molecular Faculty