Hole-Burning Spectroscopy of Heme Proteins

The student will be shadowing one of my graduate students who is investigating the magnitude and direction of electric fields generated by the protein host matrix at the active site of heme proteins (such as myoglobin). Such molecular electric fields have only recently been appreciated as a major contributor to protein function, and are thought to be involved in many aspects of protein chemistry that are critical for life, such as the reduction of the affinity of carbon monoxide (a potent endogenous poison) by heme once surrounded by the protein shell (myoglobin, hemoglobin). The experiments are carried out at low temperatures (around 1.4 K, in pumped liquid helium) and are technically very challenging. The graduate student is also working on a second, less demanding project, namely the setup of a near-field scanning optical microscope for the spatially resolved detection of ions and molecules; The student will be shadowing him during these activities as well.

Domitor – Media Ecology Project – Library of Congress Paper Print pilot and Domitor members’ website and Early Film Journals and Archive Database

As President of Domitor, an International Society for the Study of Early Cinema, I am developing the members’ area of our new website, which will include an index of early cinema journals and archival collections, as well as access to the Media Ecology Project-Library of Congress-Paper Print pilot. This latter, a collaboration between archives and scholars, provides online access to primary moving image research materials. The overall objectives and methods of the project include expanding resources, enriching metadata, and developing effective, collaborative spaces for comparative projects (e.g. my research on gesture and early women performers), while engaging in dynamic forms of scholarly production and online publishing.