Prof. Peng and Arnold received funding from the UWM Research Foundation to investigate the in vivo efficacy of novel combination therapy for cancer using ROS-activated prodrugs and prooxidants.

Current cancer drugs most often do not distinguish between malignant cells and healthy cells thus leading to the many side effects seen during cancer chemotherapy. Dr. Peng’s group has designed patented cancer pro-drugs which are selectively activated by conditions that… Read More

A R15 grant from the National Cancer Institute was awarded to Prof. Xiaohua Peng titled “Novel DNA cross-linking agents and combination strategies for tumor-specific activation”

Cancer cells are in a state of increased basal oxidative stress due to their aberrant growth. As a result, cancer cells have elevated levels of reactive oxygen species (ROS) compared to normal cells. This feature has been employed to develop… Read More

MIDD member Karyn Frick was awarded a multimillion-dollar grant to study estrogenic regulation of the hippocampal ubiquitin-proteasome system and its role in memory and structural plasticity.

Memory impairment is a defining characteristic of many neuropsychiatric disorders, however, an understanding of the complex neural mechanisms regulating hippocampal memory formation remains elusive. To investigate this neural mechanism, the National Institute of Neurological Disorders and Stroke has awarded several… Read More

Professor Qingsu Cheng has joined the MIDD

We are delighted to announce Professor Qingsu Cheng has newest  MIDD member. Dr. Cheng has previously worked as postdoctoral researcher at Lawrence Berkeley National Laboratory and Research Scientist at the University of Nevada in Reno. Dr. Cheng’s research focuses on… Read More

MIDD members are participating in the ACS SEED program

We are very proud of our MIDD members that support the ACS SEED (Summer Experience for the Economically Disadvantaged) this year. The ACS project enrolls  more than 350+ students nationally for a 8-10 week summer program at different US Universities…. Read More

MIDD members received several awards from the UWM Research Foundation

The productivity of MIDD members during the last academic year was rewarded with several awards from the UWM Research Foundation. Patent awards were granted to Dr. Karyn Frick, Distinguished Professor, Neuroscience Area Chair, Neuroscience Major Director and CSO of co-founded… Read More

MIDD partner Function Therapeutics received NSF SBIR award

Function Therapeutics, a firm performing medicinal chemistry and pharmacology at UWM since June 2022, recently received a Phase 1 SBIR award from the National Science Foundation. The grant, Structure-guided design of anti-inflammatory modulators of protease-activated receptor 1 (PAR1), will support… Read More

Simmaron Research located in the UWM chemistry building received NIH funding

We are happy to share that Avik Roy working as CSO at Simmaron Research received a NIH R21 grant in the amount of $450,000. The purpose of the grant is to study the role of autophagy-related protein ATG13 in the… Read More

New MIDD members from Department of Biomedical Science

We are delighted to announce that three excellent faculty from the Department of Biomedical Science have joined the Milwaukee Institute for Drug Discovery. Professor Janis Eells (left) is a pharmacologist with an appointment as Adjunct Professor at the Medical College… Read More

Karyn Frick and Nigel Rothfels received MSTEM award from National Institute of Aging

UWM’s STAR program seeks to help fill that gap by preparing students from underrepresented backgrounds for graduate training and careers in aging and public health. The UWM STAR program is a multi-year, cohort-based program that matches students from underrepresented backgrounds… Read More