Profile photo of Valerica Raicu

Valerica Raicu

  • Professor, Physics and Astronomy
  • Professor, Electrical Engineering

Research Interests

Professor Raicu's main research interests are:

  • Nonlinear laser spectroscopy for probing reaction dynamics and mechanical and thermal relaxation in proteins.
  • Dielectric and mechanical relaxation in complex systems.

Biographical Sketch

Valerică Raicu obtained his Physics Diploma in 1991 and his PhD in Biophysics in 1998, both from the University of Bucharest (Romania). During that time, he worked as a Research Scientist for the Institute of Physical Chemistry of Romanian Academy (1992-1996) and for Research & Design Institute for Rare and Radioactive Metals (1996-1998). The following three years he was a Research Instructor at the Department of Physiology at Kochi Medical School (Japan). In 2002, Raicu obtained a Postdoctoral Fellowship at the Departments of Chemistry and Physics and Charles H. Best Institute, University of Toronto.

Since 2004, Raicu has been at the University of Wisconsin-Milwaukee, where he holds the rank of Professor in the Department of Physics and Adjunct Professor at the Department of Biological Sciences. He served as the Chair of the Department of Physics from 2012 to 2015. Professor Raicu has developed a Biophysics course for which he also wrote the book Integrated Molecular and Cellular Biophysics (Springer, 2008). His research has been supported by the National Science Foundation (Programs: Physics of Living Systems, Major Research Instrumentation, and Partnerships for Innovation), Bradley Foundation, UWM Research Foundation, Aurora Spectral Technologies, LLC, and UWM Research Growth Initiative. He is also a Senior Researcher with the RIIO Alliance.

Selected Publications

V. Raicu, Quantization of the electromagnetic fields from single atomic or molecular radiators. Annalen der Physik (Berlin) 538 (2026) e00443, https://doi.org/10.1002/andp.202500443.
T.D. Killeen, K. Tepper, K.W. Miller, Y. Aydin, Y. Zhuo, S. Zhao, J.M. Conley, R. Tat, C. Klug, A. Marchese, V. Raicu, Q. Chen, Distinct Membrane Binding Properties of the Two Non-visual Arrestins. Communications Biology, 9 (2026) 150, https://doi.org/10.1038/s42003-025-09428-3
B. Phan, M. Stoneman, S. Sharma, T.D. Killeen, V. Raicu, I. Popa, Enabling hour-long drift correction with nanometer resolution in optical microscopy through reflection interferometry of fiducial beads. Nano Letters 25 (2025) 21095-2202. DOI: 10.1021/acs.nanolett.4c05234
V. Raicu, Derivation and physical interpretation of the general solutions to the inhomogeneous wave equations for the scalar, vector, and Hertz potentials. Annalen der Physik (Berlin) 537 (2025) 2400393.DOI: 10.1002/andp.202400393
S. Marsango, L. Jenkins, J. D. Pediani, S. J. Bradley, R. J. Ward, S. Hesse, G. Biener, M. R. Stoneman, A. B. Tobin, V. Raicu, G. Milligan, The M1 muscarinic receptor is present in situ as a ligand-regulated mixture of monomers and oligomeric complexes. Proceedings of the National Academy of Sciences 119 24, (2022) e2201103119.
Biener, Gabriel, Stoneman, Michael R., and Raicu, Valerica. “Fluorescence intensity fluctuation analysis of receptor oligomerization in membrane domains” Biophysical Journal120. (2021): 3028.
M.R. Stoneman, G. Biener, R.J. Ward, J.D. Pediani, D. Badu, I. Popa, G. Milligan, and V. Raicu, A general method to quantify ligand-driven oligomerization using fluorescence microscopy, Nature Methods, 16 (2019) 493-496
Mishra, A K., Gragg, M, Stoneman, M R., Biener, G, Oliver, Julie A., Miszta, P, Filipek, S, Raicu, Valerica, and Park, P S.“Quaternary structures of opsin in live cells revealed by FRET spectrometry” The Biochemical journal473.21 (2016): 3819-3836.
Raicu, Valerica, and Feldman, Yuri. Dielectric Relaxation in Biological Systems: Physical Principles, Methods, and ApplicationsEd. Raicu, Valerica. Oxford University Press. 2015.