Meyer, Michelle
Summary of MIDD research assistantship
The goals for the Spring semester 2022:
- Determine the cytotoxicity with liver and kidney cells of new lead compounds.
- Determine adverse CNS effects using the rotarod and open field studies.
- Determine changes in airway hyperresponsiveness (AHR) in vivo.
- Determine airway smooth muscle relaxation ex vivo (collaboration with Columbia U)
- TSLP quantification in mouse lung
- Training on LCMS 8040.
- Pharmacokinetics (PK) studies (mouse and dog study with PI560).
Undergraduate student: Anika Tylek
Michelle has been an incredible mentor throughout the past 15 months and has provided me with comprehensive instructions for every study, as well as engaging in my learning of new techniques and protocols. She has provided me with the opportunity to gain hands-on experience with many new techniques and has an exceptional knowledge regarding the background and purpose of every technique and experiment we perform. Her knowledge combined with her active guidance has helped me gain many new skills related to chemical compound and drug development and has allowed me to apply my knowledge directly in a lab setting while performing a variety of studies and assays. In the future, I plan to pursue a career in medical and pharmaceutical patent law and Michelle has been exceptional at educating me in various procedures and studies regarding the development of new drugs and the clinical and pre-clinical testing that occurs during their development.
Undergraduate Student: Molly Kiley
I am Molly Kiley, and I have been working in the Arnold Lab for the past 7 months. As Michelle has transferred into UWM’s animal facility, she has taught and guided me through cytotoxicity assays and culturing HEK293 cells. She has provided incredible academic and personal insight into both my studies and career path as an undergraduate student. In addition, Michelle’s clear and concise communication skills have helped me master cytotoxicity protocol and techniques. Adjusting to the Arnold Lab was both exciting and intimidating for me. Michelle, as well as the rest of the team, were incredibly supportive and patient as I settled into my role. Michelle and I are now preparing to start a new project, and I am excited to see how much more she has to teach me.