IManager Protocol Instructions and Link

IManager is a fully web-based system allowing users with an internet browser to securely: login and submit IBC submissions; send and receive automatic notices; view the status of active, closed, or recent submissions; and maintain the entire IBC file in one central place. It is the same system currently used for protocol submissions to the UWM IRB.

Students or someone other than the main Principal Investigator will be allowed to complete and submit forms.  However, the PI will be required to log in, review the submission, and digitally sign-off on the protocol before it will be reviewed.

Access IManager: Click here to log in to IManager

Login Instructions:

  1. UWM faculty, staff and students:  Log in using your UWM ePanther ID by selecting the Login link on the login page. An account will automatically be created the first time you log in.
  2. Non-UWM Personnel: Request an IManager account by completing the Non-UWM Personnel IManager Account Request Form. We will create an account and send you the login details as soon as possible.

New Biosafety Protocol Submission Instructions:

  1. Prior to submission, complete biosafety training, which is due every three years.
  2. Schedule and complete a biosafety lab visit (if one is not currently on file within the last calendar year).
  3. If you are working in BSL-2 or higher laboratories, make sure your laboratory Biosafety Manual is up to date and includes the risk assessments, current protocols, SOPs, and any other necessary information. You will be required to submit this with your protocol.
  4. Go to the Biosafety iManager page and click “Login to iManager”.
  5. Prepare all SOPs to include with submission and complete the Biosafety Protocol Form.
  6. Send questions/ comments to uwm-biosafety@uwm.edu.
  7. Attend the protocol review (if requested) on the meeting date- the PI should make themselves available for this scheduled time.
  8. Complete any changes (if necessary) to secure approval. Protocols ARE NOT approved until all changes have been made and the approval letter has been sent.
  9. Maintain a signed original copy of the protocol and the approval letter in your research space(s) (may be electronic).

3-Year Renewal Instructions for Protocols Approved Prior to July 2019 (Paper Forms):

  1. Prior to submission, complete biosafety training, which is due every three years.
  2. Schedule and complete a biosafety lab visit (if one is not currently on file within the last calendar year).
  3. If you are working in BSL-2 or higher laboratories, make sure your laboratory Biosafety Manual is up to date and includes the risk assessments, current protocols, SOPs, and any other necessary information. You will be required to submit this with your protocol.
  4. Go to the Biosafety iManager page and click “Login to iManager”.
  5. At the bottom of your dashboard are all of the currently approved biosafety protocols. All currently approved biosafety protocols are included in this list. If your protocol was approved before July 2019, you will need to start a new xForm while inside the protocol event. Click on the protocol number.
  6. In the left column, while viewing the event, click “Start xForm”. Select the Biosafety Protocol Initial and 3-Year Renewal Form for RESEARCH if conducting research, and the Biosafety Protocol Initial and 3-Year Renewal Form for INSTRUCTIONAL ACTIVITIES for lab course activity submissions.
  7. Prepare all SOPs to include with submission and complete the Biosafety Protocol Form. Don’t forget to click submit. If you are not the PI or lead course instructor, make sure whomever is that role reviews and signs off on the protocol for it to go to review.
  8. Send questions/ comments to uwm-biosafety@uwm.edu.
  9. Attend the protocol review (if requested) on the meeting date- the PI should make themselves available for this scheduled time.
  10. Complete any changes (if necessary) to secure approval. Protocols ARE NOT approved until all changes have been made and the approval letter has been sent.
  11. Maintain a signed original copy of the protocol and the approval letter in your research space(s) (may be electronic).

3-Year Renewal Instructions for Protocols Approved from July 2019 to present:

  1. Prior to submission, complete biosafety training, which is due every three years.
  2. Schedule and complete a biosafety lab visit (if one is not currently on file within the last calendar year).
  3. If you are working in BSL-2 or higher laboratories, make sure your laboratory Biosafety Manual is up to date and includes the risk assessments, current protocols, SOPs, and any other necessary information. You will be required to submit this with your protocol.
  4. Go to the Biosafety iManager page and click “Login to iManager”.
  5. At the bottom of your dashboard are all of the currently approved biosafety protocols. All currently approved biosafety protocols are included in this list. If your protocol was approved before July 2019, you will need to start a new xForm while inside the protocol event. Click on the protocol number.
  6. Scroll down to find the “Reference xForm” in the event. To the left of this form, click on the two pieces of paper (copy) under Actions.
  7. Select “Copy for Amendment” to submit a 3-Year Renewal. Just select the type of submission (3-Year Renewal) and then review your existing xForm. You can make any changes to the protocol as necessary before submitting for 3-year renewal review. If there are no additional changes, you can submit the existing xForm for review. Don’t forget to review and update all attachments as well. Don’t forget to click submit.
  8. If you are not the PI or lead course instructor, make sure whomever is that role reviews and signs off on the protocol for it to go to review.
  9. Send questions/ comments to uwm-biosafety@uwm.edu.
  10. Attend the protocol review (if requested) on the meeting date- the PI should make themselves available for this scheduled time.
  11. Complete any changes (if necessary) to secure approval. Protocols ARE NOT approved until all changes have been made and the approval letter has been sent.
  12. Maintain a signed original copy of the renewal and the renewal approval letter in your research space(s) (may be electronic).

Protocol Modification Instructions for Protocols Approved from July 2019 to present:

  1. Go to the Biosafety iManager page and click “Login to iManager”.
  2. At the bottom of your dashboard are all of the currently approved biosafety protocols. All currently approved biosafety protocols are included in this list. If your protocol was approved before July 2019, you will need to start a new xForm while inside the protocol event. Click on the protocol number.
  3. Scroll down to find the “Reference xForm” in the event. To the left of this form, click on the two pieces of paper (copy) under Actions.
  4. Select “Copy for Amendment” to submit a modification request and select “Modification”. Enter in any changes as needed on the xForm. 3-Year Renewal. Just select the type of submission (3-Year Renewal) and then review your existing xForm. Don’t forget to click submit.
  5. If you are not the PI or lead course instructor, make sure whomever is that role reviews and signs off on the protocol for it to go to review.
  6. Send questions/ comments to uwm-biosafety@uwm.edu.
  7. Attend the protocol review (if requested) on the meeting date- the PI should make themselves available for this scheduled time.
  8. Complete any changes (if necessary) to secure approval. Protocols ARE NOT approved until all changes have been made and the approval letter has been sent.
  9. Maintain an updated copy of the modification and the modification approval letter in your research space(s) (may be electronic). Note that your expiration date will not change, the original approval period will stay the same. This only approves changes made within the approval period.

Biosafety Protocol Approval Requirements

Using the link below, you can learn more about the minimum requirements for biosafety protocol approval, as well as guidelines for work with commonly used infectious agents/ materials at UWM.

IBC and Biosafety Program Requirements for Biosafety Protocol Approval