Poster Presentations
Michelle J. Meyer, Daniel A. Webb, Md Shadiqur Rashid Roni, Sarah Swartwout, Ahmad Masoud, Leggy A. Arnold “Characterization of microencapsulated PI301” Milwaukee Analytical Chemistry Conference, September 11th, 2023.
Michelle J. Meyer, Daniel A. Webb, Md Shadiqur Rashid Roni, Sarah Swartwout, Ahmad Masoud, Leggy A. Arnold, “A comparison of mice and dog pharmacokinetics of novel drug candidates”, Chemistry and Biochemistry Research Symposium, UWM, Milwaukee, April 28th, 2023.
Michelle J. Meyer, Daniel A. Webb, Md Shadiqur Rashid Roni, Sarah Swartwout, Ahmad Masoud, Leggy A. Arnold, “A comparison of mice and dog pharmacokinetics of novel drug candidates”, MIDD symposium 2023, February 17th, 2023.
Michelle Meyer, Nicolas N. Zahn, Leggy A. Arnold “Determination of Lung TSLP Levels in OVA s/c Mice Treated Orally with GABAA receptor modulator MIDD0301” Chemistry and Biochemistry Research Symposium, UWM, Milwaukee, April 22nd, 2022.
Michelle Meyer, Nicolas M. Zahn, James M. Cook, Douglas C. Stafford and Leggy A. Arnold, “Cell Viability, Motor Performance, and Behavioral Assessments of New Drug Candidates” UW System Symposium, UW Whitewater, April 28th, 2021.
Michelle Meyer, Nicolas M. Zahn, James M. Cook, Douglas C. Stafford and Leggy A. Arnold, “Cell Viability, Motor Performance, and Behavioral Assessments of New Drug Candidates” Chemistry and Biochemistry Research Symposium, UWM, Milwaukee, April 23rd, 2021.
Selected Publications
Daniel A Webb,
Michelle J Meyer, Kayode M Medubi, Anika S Tylek, Gene T Yocum, M S Rashid Roni, Nicolas M Zahn, Sarah A Swartwout, Ahmad K Masoud, Charles W Emala, Douglas C Stafford, Leggy A Arnold
“Design, Synthesis, and Biological Evaluation of Novel Spiro Imidazobenzodiazepines to Identify Improved Inhaled Bronchodilators” J Med Chem,
2023, 66(14), 9853-9865.
Kamal P. Pandey, Branka Divović, Farjana Rashid, Lalit K. Golani, Rok Cerne, Nicolas M. Zahn,
Michelle J. Meyer, Leggy A. Arnold, Dishary Sharmin, Md Yeunus Mian, Jodi L. Smith, Xingjie Ping, Xiaoming Jin, Arnold Lippa, V V N Phani Babu Tiruveedhula, James M. Cook, Miroslav Savic, Jeffrey M. Witkin
“Structural analogs of the GABAkine (5-(8-ethynyl-6-(pyridin-2-yl)-4H-benzo[ f ]imidazole[1,5-α ] [1,4]diazepin-3-yl) oxazole) ( KRM-II-81) are orally bioavailable anticonvulsants without sedation” J Pharmacol Exp Ther 2023, 385 (1), 50-61.
Xingjie Ping,
Michelle J. Meyer, Nicolas M. Zahn, Lalit K. Golani, Dishary Sharmin, Kamal P. Pandey, Sepideh Revanian, Prithu Mondal, Xiaoming Jin, Leggy A. Arnold, Rok Cerne, James M. Cook, Branka Divović, Miroslav M. Savić, Arnold Lippa, Jodi L. Smith, Jeffrey M. Witkin
“Comparative anticonvulsant activity of the GABAkine KRM-II-81 and a deuterated analog” Drug Development Research 2023.
Lalit K Golani, Branka Divović, Dishary Sharmin, Kamal P Pandey, Md Yeunus Mian, Rok Cerne, Nicolas M Zahn,
Michelle J Meyer, Veera V N P B Tiruveedhula, Jodi L Smith, Xingjie Ping, Xiaoming Jin, Arnold Lippa, Jeffrey M Schkeryantz, Leggy A Arnold, James M Cook, Miroslav M Savić and Jeffrey M Witkin “
Metabolism, pharmacokinetics, and anticonvulsant activity of a deuterated analog of the α2/3-selective GABAkine KRM-II-81” Biopharmaceutics and Drug Disposition
2022, 43(2), 66-75.
M.S. Rashid Roni, Nicolas M. Zahn, Gene T. Yocum, Daniel A. Webb, Md Yeunus Mian,
Michelle J. Meyer, Anika S. Tylek, James M. Cook, Charles W. Emala, Douglas C. Stafford and Leggy A. Arnold "
Comparative pharmacodynamic and pharmacokinetic study of MIDD0301 and its (S) enantiomer" Drug Development Research
2022, 83(4), 979-992.
Nicolas M. Zahn, M.S. Rashid Roni, Gene T. Yocum,
Michelle J. Meyer, Daniel A. Webb, Md Yeunus Mian, James M. Cook, Douglas C. Stafford, Charles W. Emala, and Leggy A. Arnold "
Development of inhaled GABA(A) receptor modulators to improve airway function in bronchoconstrictive disorders" ACS Pharmacology& Translational Science 2022, 5(2), 80-88.