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Michelle Meyer

  • Fellow, Chemistry & Biochemistry

Education

PhD, Chemistry, University of Wisconsin-Milwaukee, 2025

BS, Biochemistry & Psychology, Minor in Biology, University of Wisconsin-Milwaukee, 2021

Poster Presentations

1.    "Medical Countermeasure to Chlorine-Induced Lung Injury Targeting GABAA Receptors" – MIDD/Milwaukee Analytical Chemistry Conference, Milwaukee, Dec 7, 2024. (Michelle J. Meyer, Leggy A. Arnold)

2.    "Development of a Novel Oral Treatment for Atopic Dermatitis" – Chemistry and Biochemistry Research Symposium, Milwaukee, May 9–10, 2024. (Michelle J. Meyer, Daniel A. Webb, Douglas C. Stafford, Leggy A. Arnold)

3.    "Novel Oral Treatment for Atopic Dermatitis: Allosteric Modulation of GABAA Receptor Signaling" – American Association of Immunologists Conference, Chicago, May 3–7, 2024. (Michelle J. Meyer, Daniel A. Webb, Douglas C. Stafford, Leggy A. Arnold)

4.    "Development of a Novel Oral Treatment for Atopic Dermatitis" – American Academy of Allergy, Asthma & Immunology Conference, Washinton D.C., Feb 23–27, 2024. (Michelle J. Meyer, Daniel A. Webb, Douglas C. Stafford, Leggy A. Arnold)

5.    "Microencapsulation as a Strategy for Improved Drug Pharmacokinetics" – Milwaukee Analytical Chemistry Conference, Sep 11, 2023. (Michelle J. Meyer, Daniel A. Webb, Md Shadiqur Rashid Roni, Sarah Swartwout, Ahmad Masoud, Leggy A. Arnold)

6.    "Comparison of Mice and Dog Pharmacokinetics of Novel Drug Candidates" – Chemistry and Biochemistry Research Symposium, Milwaukee, Apr 28, 2023. (Michelle J. Meyer, Daniel A. Webb, Md Shadiqur Rashid Roni, Sarah Swartwout, Ahmad Masoud, Leggy A. Arnold)

7.    "Comparison of Mice and Dog Pharmacokinetics of Novel Drug Candidates" – MIDD Symposium, Milwaukee, Feb 17, 2023. (Michelle J. Meyer, Daniel A. Webb, Md Shadiqur Rashid Roni, Sarah Swartwout, Ahmad Masoud, Leggy A. Arnold)

8.    "Lung TSLP Levels in OVA s/c Mice Treated with GABAA Receptor Modulator MIDD0301" – Chemistry and Biochemistry Research Symposium, Milwaukee, Apr 22, 2022. (Michelle J. Meyer, Nicolas N. Zahn, Leggy A. Arnold)

9.    "Cell Viability, Motor Performance, and Behavioral Assessments of New Drug Candidates" – UW System Symposium, Whitewater, Apr 28, 2021. (Michelle J. Meyer, Nicolas M. Zahn, James M. Cook, Douglas C. Stafford, Leggy A. Arnold)

10. "Cell Viability, Motor Performance, and Behavioral Assessments of New Drug Candidates" – Chemistry and Biochemistry Research Symposium, Milwaukee, Apr 23, 2021. (Michelle J. Meyer, Nicolas M. Zahn, James M. Cook, Douglas C. Stafford, Leggy A. Arnold)

Selected Publications

Daniel A Webb, Michelle J Meyer, Kayode M Medubi, Anika S Tylek, Gene T Yocum, M S Rashid Roni, Nicolas M Zahn, Sarah A Swartwout, Ahmad K Masoud, Charles W Emala, Douglas C Stafford, Leggy A Arnold “Design, Synthesis, and Biological Evaluation of Novel Spiro Imidazobenzodiazepines to Identify Improved Inhaled Bronchodilators” J Med Chem, 2023, 66(14), 9853-9865.
Kamal P. Pandey, Branka Divović, Farjana Rashid, Lalit K. Golani, Rok Cerne, Nicolas M. Zahn, Michelle J. Meyer, Leggy A. Arnold, Dishary Sharmin, Md Yeunus Mian, Jodi L. Smith, Xingjie Ping, Xiaoming Jin, Arnold Lippa, V V N Phani Babu Tiruveedhula, James M. Cook, Miroslav Savic, Jeffrey M. Witkin “Structural analogs of the GABAkine (5-(8-ethynyl-6-(pyridin-2-yl)-4H-benzo[ f ]imidazole[1,5-α ] [1,4]diazepin-3-yl) oxazole) ( KRM-II-81) are orally bioavailable anticonvulsants without sedation” J Pharmacol Exp Ther 2023, 385 (1), 50-61.
Xingjie Ping, Michelle J. Meyer, Nicolas M. Zahn, Lalit K. Golani, Dishary Sharmin, Kamal P. Pandey, Sepideh Revanian, Prithu Mondal, Xiaoming Jin, Leggy A. Arnold, Rok Cerne, James M. Cook, Branka Divović, Miroslav M. Savić, Arnold Lippa, Jodi L. Smith, Jeffrey M. Witkin “Comparative anticonvulsant activity of the GABAkine KRM-II-81 and a deuterated analog” Drug Development Research 2023.
Lalit K Golani, Branka Divović, Dishary Sharmin, Kamal P Pandey, Md Yeunus Mian, Rok Cerne, Nicolas M Zahn, Michelle J Meyer, Veera V N P B Tiruveedhula, Jodi L Smith, Xingjie Ping, Xiaoming Jin, Arnold Lippa, Jeffrey M Schkeryantz, Leggy A  Arnold, James M Cook, Miroslav M Savić and Jeffrey M Witkin “Metabolism, pharmacokinetics, and anticonvulsant activity of a deuterated analog of the α2/3-selective GABAkine KRM-II-81” Biopharmaceutics and Drug Disposition 2022, 43(2), 66-75.
M.S. Rashid Roni, Nicolas M. Zahn, Gene T. Yocum, Daniel A. Webb, Md Yeunus Mian, Michelle J. Meyer, Anika S. Tylek, James M. Cook, Charles W. Emala, Douglas C. Stafford and Leggy A. Arnold "Comparative pharmacodynamic and pharmacokinetic study of MIDD0301 and its (S) enantiomer" Drug Development Research 2022, 83(4), 979-992.
Nicolas M. Zahn, M.S. Rashid Roni, Gene T. Yocum, Michelle J. Meyer, Daniel A. Webb, Md Yeunus Mian, James M. Cook, Douglas C. Stafford, Charles W. Emala, and Leggy A. Arnold "Development of inhaled GABA(A) receptor modulators to improve airway function in bronchoconstrictive disorders" ACS Pharmacology& Translational Science 2022, 5(2), 80-88.

UWM Land Acknowledgement: We acknowledge in Milwaukee that we are on traditional Potawatomi, Ho-Chunk and Menominee homeland along the southwest shores of Michigami, North America’s largest system of freshwater lakes, where the Milwaukee, Menominee and Kinnickinnic rivers meet and the people of Wisconsin’s sovereign Anishinaabe, Ho-Chunk, Menominee, Oneida and Mohican nations remain present.   |   To learn more, visit the Electa Quinney Institute website.