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Portrait of Fang Yao Stephen Hou

Fang Yao Stephen Hou, PhD, MB(ASCP)QCYM, MLS(AS

  • Clinical Assistant Professor, Biomedical Sciences Lab Programs


Ph D PsychoNeuroImmunology University of Wisconsin-Madison 1996
MS Microbiology and Immunology National Yang-Ming University 1987
BS Medical Technology Yang-Ming University 1985

Interests & Expertise

Stephen Hou enjoys sharing knowledge and experiences with students. He has many years of experience in higher education. He has taught several courses in medical laboratory science including hematology, clinical chemistry, body fluids, urine analysis, molecular diagnosis and forensic science. With his extensive training in flow cytometry and microscopy, he has been involved in research areas like cancer biology and psychoneuroimmunology. One of his latest projects is salivary cytomics - to characterize various cellular elements in saliva, as a model to study mucosal immunity. With his diverse work experience in the past ranging from academic to industrial environments, he loves to help students acquire practical job skills and reach their future educational goals.

Selected Publications

Wang, I., Kapellush, J., Hou, F., & Mohammad, R. (2021). Trends in TC/HDL and LDL/HDL Ratios across the Age Span: Data from the 2007-2018 National Health and Nutrition Examination Survey (NHANES). Asian Journal of Complementary and Alternative Medicine, 9(1), 6-15.
Kao, C. H., Chen, H., Hou, F., Chang, S. W., Chang, C. W., Lai, C. S., Chen, C. P., He, Y. Y., Lin, S. R., Hsieh, K. M., & Lin, M. H. (2015). Fabrication of multianalyte CeO2 nanograin electrolyte-insulator-semiconductor biosensors by using CF4 plasma treatment. Sensing and Bio-Sensing Research, 5, 71-77.
Rosewald, M., Hou, F., Mututuvari, T., Harkins, A. L., & Tran, C. T. (2014). Cellulose-Chitosan-Keratin Composite Materials: Synthesis, Immunological and Antibacterial Properties. ECS transactions, 64(4), 499-505.
Wang, S. R., Hou, F., Wang, A., Chang, Y. I., Liu, C. T., Tsay, G. I., & Wei, C. C. (2009). The Significance of Arginase I Administration on the Survial of Mice Bearing NS-1 Myeloma Cells. Journal of Surgical Research, 151(1), 28-32.
Tan, Z., Sun, X., Hou, F., Oh, H. W., Hilgenberg, L. G., Hol, E. M., van Leeuwen, F. W., Smith, M. A., O'Dowd, D. K., & Schreiber, S. S. (2007). Mutant ubiquitin found in Alzheimer's disease causes neuritic beading of mitochondria in association with neuronal degeneration. Cell Death and Differentiation, 14(10), 1721-1732.
Brain, J. F., Wong, N., Pandhoh, M. T., Truong, S., Diaz, K., Chao, S., Hou, F., & Gardiner, D. (2005). Identification of chondrocyte proliferation following laser irradiation, thermal injury, and mechanical trauma. Lasers in Surgery and Medicine, 37, 89-96.
Fuja, T., Hou, F., & Bryant, P. (2004). A multiplex microsphere bead assay for comparative RNA expression analysis using flow cytometry. Journal of Biotechnology, 108(3), 193-205.
Ni, Z., Hou, F., Barton, C. H., & Vaziri, N. D. (2004). Lead exposure raises superoxide and hydrogen peroxide in human endothelial and vascular smooth muscle cells. Kidney International, 66(6), 2329-2336.
Leung, L., Kwong, M., Hou, F., Lee, C., & Chan, J. Y. (2003). Deficiency of the Nrf1 and Nrf2 transcription factors results in early embryonic lethality and severe oxidative stress. Journal of Biological Chemistry, 278(48), 48021-48029.
Suen, Y., Lee, S. M., Aono, F., Hou, F., Loudaovaris, M., Ofstein, G., & Bender, J. G. (2001). Comparison of monocyte enrichment by immuno-magnetic depletion or adherence for the clinical-scale generation of DC. Cytotherapy, 3(5), 265-275.
Coe, C. L., Hou, F., & Clarke, A. S. (1996). Fluoxetine Treatment Alters Leukocyte trafficking in the Intrathecal Compartment of the Young Primate. Biological Psychiatry, 40(5), 361-367.
Hou, F., Coe, C. L., & Erickson, C. (1996). Leukocyte trafficking in Free-Flowing Cerebrospinal Fluid of Normal Rhesus Macaques. Journal of Medical Primatology, 25(1), 8-13.
Hou, F., Coe, C. L., & Erickson, C. (1996). Psychological Disturbance Differentially Alters CD4+ and CD8+ Leukocytes in the Blood and Intrathecal Compartments. Journal of Neuroimmunology, 68, 13-18.


Hou, F. (April 2018). Schistocyte Counting: ICSH Guidelines, Automatic Methods & Beyond. ASCLS-WI state annual conference, Milwaukee WI.
Cambre, M., Wang, B., Hou, F., Lee, H., Harper, L., & Huang, Y. (March 2018). NiO and NiOH Nanoparticles Induce Oxidative Stress-Mediated Cellular Signaling Deregulation. 57th Annual Meeting of the Society of Toxicology, San Antonio, Texas..
Chen, Z., & Hou, F. (2014). First Morning Saliva and Presence of RBCs or WBCs to Evaluate Oral Health - Method Development. , Ft. Lauderdale, FL.
Chen, Z., & Hou, F. (2013). Salivary Cytomics - a Useful Clinical Diagnostic Tool for Dental Professionals. , San Diego, CA.
Hou, F. (2012). Cellular Elements in Preserved Saliva. , Los Angeles, CA.
Hou, F., Tamsen, C., Lee, D., & Dentino, A. (2011). Visualizing Cellular Elements in Saliva to Study Oral Mucosal Immunity. , Chicago, IL.
Hou, F. (2010). Saliva Samples Collected from Various Methods are Excellent Materials for 4 September 2016  Cellular Analysis. American Society of Clinical Laboratory Science, Anaheim, CA.
Suen, Y., Hou, F., Aono, F., & Bender, J. (1999). Coating gas permeable bags with antibodies to CD14 enhances the generation of monocyte derived dendritic cells. , New Orleans, Louisiana.
Baratelli, F., Hou, F., Aono, F., Loudovaris, M. F., & Benders, J. (1999). Comparison of CD40L, IFN-[alpha] and Calcium Ionophore as Inducers of the Terminal Maturation of CD34-Derived Dendritic Cells. , New Orleans, Louisiana.
Qian, J. X., Van de Ven, F., Bracho, F., Hou, F., & Cairo, M. S. (1998). Ex-vivo generation of dendritic cells (DC) from cord blood (CB) adherent mononuclear cells (MNC) using serum-free medium with TGF-beta1, GM-CSF, IL- 4, TNF-alpha, and Flt-3. American Association of Cancer Research, Indian Wells, CA.
Hou, F. (1998). Serum-free/protein-free enrichment of dendritic cell precursors with plastic adherence. American Society of Hematology, Miami Beach, FL.
Hou, F., Seth, T., Zhu, E., Suen, Y., & Cairo, M. S. (1998). Molecular and chemotherapy purging by antisense oligonucleotides and chemotherapy of Burkitt's lymphoma seeded peripheral blood stem cells, resulted in 2.6 log tumor depletion by both apoptotic and non-apoptotic mechanisms. , Indian Wells, CA.
Bracho, F., Van de Ven, C., Qian, J. X., Hou, F., & Cairo, M. S. (1998). The use of autologous plasmas to ex-vivo expand dendritic cells (DC) from cord blood (CB) mononuclear cells (MNC) stimulated with FLT-3, GM- CSF, TNF-alpha, IL-4. , Indian Wells, CA.
van de Ven, C., Qian, J. X., Hou, F., Bracho, F., Smith, D., Smith, A., & Cairo, M. S. (1997). Significant ex vivo expansion of dendritic cells from cord blood mononuclear cells (MNC) with FLT-3, GM-CSF, IL-4 and TNF alpha: Implications for immunotherapy post umbilical cord blood transplant. , San Diego, CA.
Hou, F., Suen, Y., Seth, T., Zhu, E., Bailey, T., & Cairo, M. S. (1997). Specificity of c-myc rearrangement and complimentary antisense oligonucleotide is associated with unique patterns of apoptotic and non-apoptotic cell death in Burkitt's Lymphoma. , San Diego, CA.

Professional Memberships