{"id":6944,"date":"2023-02-13T13:25:00","date_gmt":"2023-02-13T19:25:00","guid":{"rendered":"https:\/\/uwm.edu\/physics\/?post_type=tribe_events&#038;p=6944"},"modified":"2023-04-05T10:16:17","modified_gmt":"2023-04-05T15:16:17","slug":"physics-colloquium-dr-horia-petrache","status":"publish","type":"tribe_events","link":"https:\/\/uwm.edu\/physics\/event\/physics-colloquium-dr-horia-petrache\/","title":{"rendered":"Physics Colloquium &#8211; Dr. Horia Petrache"},"content":{"rendered":"<p><strong>Dr. Horia Petrach<\/strong>, Department of Physics, Indiana &amp; Purdue Universities<\/p>\n<p><strong>Interactions of Neuromodulators with Model Lipid Membranes<\/strong><\/p>\n<p>Neurotransmitters and neuromodulators typically function by binding to specialized receptors in neuronal membranes. In this work, we study two different neurotransmitters that also function as neuromodulators, namely dopamine (DA) and adenosine triphosphate (ATP). Dopamine is best known as the feel-pleasure hormone while ATP is best known for being the source of energy in the cell. Using a combination of scattering and spectroscopic methods, we show that both DA and ATP have an affinity to lipid membranes lacking specialized receptors. In particular, by x-ray scattering and NMR spectroscopy we show that both DA and ATP interact with lipid headgroups at the membrane-water interface. As a consequence, the membrane surface potential is modified as measured by Dynamic Light Scattering. Our results can contribute to understanding the role of lipid membranes in neuromodulation.<\/p>\n<p>The event flyer is available for download <a href=\"https:\/\/uwm.edu\/physics\/wp-content\/uploads\/sites\/63\/2023\/04\/Petrache-04-28-2023-Flyer.pdf\">here<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p><strong>Dr. Horia Petrach<\/strong>, Department of Physics, Indiana &amp; Purdue Universities<\/p>\n<p><strong>Interactions of Neuromodulators with Model Lipid Membranes<\/strong><\/p>\n<p>Neurotransmitters and neuromodulators typically function by binding to specialized receptors in neuronal membranes. In this work, we study two different neurotransmitters that also function as neuromodulators, namely dopamine (DA) and adenosine triphosphate (ATP). Dopamine is best known as the feel-pleasure hormone while ATP is best known for being the source of energy in the cell. <\/p>\n","protected":false},"author":9647,"featured_media":0,"template":"","meta":{"_acf_changed":false,"_tribe_events_status":"","_tribe_events_status_reason":"","_tribe_events_is_hybrid":"","_tribe_events_is_virtual":"","_tribe_events_virtual_video_source":"","_tribe_events_virtual_embed_video":"","_tribe_events_virtual_linked_button_text":"","_tribe_events_virtual_linked_button":"","_tribe_events_virtual_show_embed_at":"","_tribe_events_virtual_show_embed_to":[],"_tribe_events_virtual_show_on_event":"","_tribe_events_virtual_show_on_views":"","_tribe_events_virtual_url":"","footnotes":"","uwm_wg_additional_authors":[]},"tags":[],"tribe_events_cat":[58],"class_list":["post-6944","tribe_events","type-tribe_events","status-publish","hentry","tribe_events_cat-physics-colloquia","cat_physics-colloquia"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.3 (Yoast SEO v27.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Physics &amp; Astronomy<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/uwm.edu\/physics\/event\/physics-colloquium-dr-horia-petrache\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Physics Colloquium - Dr. Horia Petrache\" \/>\n<meta property=\"og:description\" content=\"Dr. Horia Petrach, Department of Physics, Indiana &amp; Purdue Universities  Interactions of Neuromodulators with Model Lipid Membranes  Neurotransmitters and neuromodulators typically function by binding to specialized receptors in neuronal membranes. In this work, we study two different neurotransmitters that also function as neuromodulators, namely dopamine (DA) and adenosine triphosphate (ATP). 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