{"id":4132,"date":"2018-05-29T10:18:24","date_gmt":"2018-05-29T15:18:24","guid":{"rendered":"https:\/\/uwm.edu\/physics\/?post_type=tribe_events&#038;p=4132"},"modified":"2018-05-29T10:18:24","modified_gmt":"2018-05-29T15:18:24","slug":"biophysics-talk-professor-abhishek-singharoy","status":"publish","type":"tribe_events","link":"https:\/\/uwm.edu\/physics\/event\/biophysics-talk-professor-abhishek-singharoy\/","title":{"rendered":"Biophysics Talk &#8211; Professor Abhishek Singharoy"},"content":{"rendered":"<p><strong>Abhishek Singharoy<\/strong>, Assistant Professor, Center for Applied Structural Discovery, Biodesign Institute at Arizona State University.<\/p>\n<p><strong>Computing Free-Energy Landscapes from Molecular Dynamics Simulations<\/strong><\/p>\n<p>The most probable pathways of structural transition in biomolecular complexes follow minimum free-energy pathways.  Employing an implicit scheme for solving the Langevin dynamics equation, called the string method, these pathways are determined for structural transitions in molecular motors. The underlying multidimensional thermodynamic landscape is probed to determine experimentally measurable quantities such as, binding affinity, turnover rates, and energy conversion efficiencies.<\/p>\n","protected":false},"excerpt":{"rendered":"<p><strong>Abhishek Singharoy<\/strong>, Assistant Professor, Center for Applied Structural Discovery, Biodesign Institute at Arizona State University.<\/p>\n<p><strong>Computing Free-Energy Landscapes from Molecular Dynamics Simulations<\/strong><\/p>\n<p>The most probable pathways of structural transition in biomolecular complexes follow minimum free-energy pathways.  Employing an implicit scheme for solving the Langevin dynamics equation, called the string method, these pathways are determined for structural transitions in molecular motors. The underlying multidimensional thermodynamic landscape is probed to determine experimentally measurable quantities such as, binding affinity, turnover rates, and energy conversion efficiencies.<\/p>\n","protected":false},"author":9647,"featured_media":0,"template":"","meta":{"_acf_changed":false,"_tribe_events_status":"","_tribe_events_status_reason":"","_tribe_events_is_hybrid":"","_tribe_events_is_virtual":"","_tribe_events_virtual_video_source":"","_tribe_events_virtual_embed_video":"","_tribe_events_virtual_linked_button_text":"","_tribe_events_virtual_linked_button":"","_tribe_events_virtual_show_embed_at":"","_tribe_events_virtual_show_embed_to":[],"_tribe_events_virtual_show_on_event":"","_tribe_events_virtual_show_on_views":"","_tribe_events_virtual_url":"","footnotes":"","uwm_wg_additional_authors":[]},"tags":[],"tribe_events_cat":[57],"class_list":["post-4132","tribe_events","type-tribe_events","status-publish","hentry","tribe_events_cat-biophysics-seminars","cat_biophysics-seminars"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Physics &amp; Astronomy<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/uwm.edu\/physics\/event\/biophysics-talk-professor-abhishek-singharoy\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Biophysics Talk - Professor Abhishek Singharoy\" \/>\n<meta property=\"og:description\" content=\"Abhishek Singharoy, Assistant Professor, Center for Applied Structural Discovery, Biodesign Institute at Arizona State University.  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