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DTSTART;TZID=America/Chicago:20161130T140000
DTEND;TZID=America/Chicago:20161130T150000
DTSTAMP:20260619T134642
CREATED:20161130T160148Z
LAST-MODIFIED:20161130T160742Z
UID:10382468-1480514400-1480518000@uwm.edu
SUMMARY:Colloquium: Ashish Mishra
DESCRIPTION:This special Physics department colloquium is scheduled for Wednesday 11/30/16 at 2:00 PM in the Kenwood Interdisciplinary Research Complex (KIRC) Room KEN 2035. Anyone is welcome. \nInvestigation of Membrane Receptors’ Oligomers Using Fluorescence Resonance Energy Transfer and Multiphoton Microscopy in Living Cells\nAshish Mishra\, PhD Candidate/UWM Dept. of Physics \nInvestigating quaternary structure (oligomerization) of macromolecules (such as proteins and nucleic acids) in living systems (in vivo) has been a great challenge in biophysics\, due to molecular diffusion\, fluctuations in several biochemical parameters such as pH\, quenching of fluorescence by oxygen (when fluorescence methods are used)\, etc. \nWe studied oligomerization of membrane receptors in living cells by means of Fluorescence (Förster) Resonance Energy Transfer (FRET) using fluorescent markers and two photon excitation fluorescence micro-spectroscopy.  Using suitable FRET models\, we are able to determine the stoichiometry and quaternary structure of various macromolecular complexes. In this talk\, I will present results of the above-mentioned study for two membrane receptors: (1) sigma-1 receptor and (2) rhodopsin\, described below: \n1)	 Sigma-1 receptors are molecular chaperone proteins\, which also regulate ion channels. S1R seems to be involved in substance abuse\, as well as several diseases such as Alzheimer’s. \n2)	 Rhodopsin is a prototypical G protein coupled receptor (GPCR) and is directly involved in vision. GPCRs form a large family of receptors that participate in cell signaling by responding to external stimuli such as drugs\, thus being a major drug target (more than 40% drugs target GPCRs).
URL:https://uwm.edu/physics/event/colloquium-ashish-mishra/
LOCATION:KIRC KEN 2035\, 3135 N. Maryland Ave.\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Physics Colloquia
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DTSTART;TZID=America/Chicago:20161111T090000
DTEND;TZID=America/Chicago:20161111T100000
DTSTAMP:20260619T134642
CREATED:20161110T141540Z
LAST-MODIFIED:20161110T142203Z
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SUMMARY:Colloquium: Binod Manandhar
DESCRIPTION:This special Physics department colloquium is scheduled for Friday 11/11/16 at 9:00 AM in the Kenwood Interdisciplinary Research Complex (KIRC) Room KEN 2035. Anyone is welcome. \nReduction of Graphene Oxide & Soluble Molybdenum Oxide Mixture in High Vacuum for Production of Materials for Energy Storage Device\nBinod Manandhar\, PhD Candidate/UWM Dept. of Physics \nGraphene\, a two dimensional honey comb structure of carbon due to its high electrical and thermal conductivity\, and high specific surface area\, is an excellent candidate for nano-electronics and energy storage.  However\, it is very difficult and expensive to produce a single layered graphene by the traditional method of mechanical exfoliation of highly oriented pyrolytic graphite (HOPG).  It is mainly manufactured by chemical vapour deposition (CVD) or more economically by chemical exfoliation of graphite by Hummer’s modified method.  But there is a major disadvantage in using the chemical exfoliation\, instead of forming a single layer of pure graphene\, a non-stoichiometric and insulating graphene oxide (GO) is formed.  GO further needs to be reduced into graphene by either chemical or thermal method.  \nIn our work\, we have demonstrated the thermal reduction of GO in vacuum chamber (10-6 torr) in presence of soluble oxide of Molybdenum\, named as Molybdenum blue (Mo blue)\, at low temperature (550-650 °C).  During thermal reduction\, we were able to produce nanocomposite of MoO2 and reduced GO.  Due to its distorted rutile structure MoO2 has metal like conductivity.  It has high specific charge capacity.  The nano composite was highly electrostatic\, has very high surface to volume ratio\, so it has great potential for making anode for lithium ion batteries (LIBs).
URL:https://uwm.edu/physics/event/colloquium-binod-manandhar/
LOCATION:KIRC KEN 2035\, 3135 N. Maryland Ave.\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Physics Colloquia
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BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20160421T123000
DTEND;TZID=America/Chicago:20160421T133000
DTSTAMP:20260619T134642
CREATED:20160420T194049Z
LAST-MODIFIED:20160420T195804Z
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SUMMARY:Colloquium: Luis da Silva
DESCRIPTION:This special Physics department PhD colloquium is scheduled for Thursday (4/21/2016) afternoon at 12:30 pm in KIRC KEN 2035. Coffee and cookies will be served at 12:00 NOON on KIRC 3rd floor. Anyone is welcome. \nIntersections of Astrophysics\, Cosmology and Particle Physics\nLuis da Silva UWM Physics PhD Candidate \n    With the success of the Large Hadron Collider (LHC) at CERN\, a new era of discovery has just begun. The SU(3)C  x SU(2)L x U(1)Y Standard Model (SM) of electroweak and strong interactions has once again endured intensive scrutiny. Most spectacularly\, the recent discovery of a particle which seems to be the SM Higgs has possibly plugged the final remaining experimental hole in the SM\, cementing the theory further.  Adding more to the story\, the IceCube Collaboration recently reported the discovery of extraterrestrial neutrinos\, heralding a new era in astroparticle physics. The collaboration was able to isolate 36 events in 3 years of data\, with energies between 30 TeV ≤  Ev ≤ 2 PeV. These events are consistent with an isotropic distribution in the sky\, and a purely atmospheric explanation of the data can be excluded at 5.7σ. \n    However\, problems still exist. Cosmological observations concerning Dark Matter and the expansion rate of the Universe have shown us our picture of the basic constituents of the Universe and the interactions among them are not fully understood. In addition\, the determination of the origin of high energy neutrinos has proven to be a quite formidable question\, with many possible candidates for sources. In this work\, we take a global approach to understanding the laboratory\, astrophysical and cosmological observations\, and study the connections and possible paths towards the final solution of these problems.
URL:https://uwm.edu/physics/event/colloquium-luis-da-silva/
LOCATION:KIRC KEN 2035\, 3135 N. Maryland Ave.\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Physics Colloquia
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