BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//Physics & Astronomy - ECPv6.16.3//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-WR-CALNAME:Physics & Astronomy
X-ORIGINAL-URL:https://uwm.edu/physics
X-WR-CALDESC:Events for Physics & Astronomy
REFRESH-INTERVAL;VALUE=DURATION:PT1H
X-Robots-Tag:noindex
X-PUBLISHED-TTL:PT1H
BEGIN:VTIMEZONE
TZID:America/Chicago
BEGIN:DAYLIGHT
TZOFFSETFROM:-0600
TZOFFSETTO:-0500
TZNAME:CDT
DTSTART:20250309T080000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0500
TZOFFSETTO:-0600
TZNAME:CST
DTSTART:20251102T070000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:-0600
TZOFFSETTO:-0500
TZNAME:CDT
DTSTART:20260308T080000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0500
TZOFFSETTO:-0600
TZNAME:CST
DTSTART:20261101T070000
END:STANDARD
BEGIN:DAYLIGHT
TZOFFSETFROM:-0600
TZOFFSETTO:-0500
TZNAME:CDT
DTSTART:20270314T080000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:-0500
TZOFFSETTO:-0600
TZNAME:CST
DTSTART:20271107T070000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20260522T153000
DTEND;TZID=America/Chicago:20260522T170000
DTSTAMP:20260613T174715
CREATED:20260219T153653Z
LAST-MODIFIED:20260401T154020Z
UID:10435393-1779463800-1779469200@uwm.edu
SUMMARY:Physics Colloquium - Jorge Alegre-Cebollada
DESCRIPTION:Titin-based Molecular Underpinnings of Skeletal and Cardiac Muscle Function\nJorge Alegre-Cebollada\, PhD\nAssociate Professor & Group Leader\, CNIC (Spanish National Center for Cardiovascular Research) \nTitin is the largest protein in the human body.  The function of the protein is not any smaller: it is critical for the contractile activity of muscles in the skeletal system and in the heart.  In my presentation\, I will introduce fundamental concepts that link titin nanomechanics with the macroscopic mechanical function of muscle.  I will focus on our recent data demonstrating dysregulation of titin nanomechanics that can contribute to increased risk of heart failure in diabetic patients.  \nTowards the end of my presentation\, I will describe how to harness titin mechanics to develop hydrogels with tailored viscoelasticity for applications in cell mechanobiology.  Time permitting\, I will discuss about new models to study titin mechanics in living matter.
URL:https://uwm.edu/physics/event/physics-colloquium-jorge-alegre-cebollada/
LOCATION:Chemistry 108\, 2050 E Kenwood Blvd\, Milwaukee\, WI\, 53201\, United States
CATEGORIES:Physics Colloquia
X-TRIBE-STATUS:
END:VEVENT
END:VCALENDAR