Ph D Pharmacology Case Western Reserve University 2010
BS Biochemistry Spring Hill College 2004
Interest & Expertise
Dr. Elizabeth Liedhegner is a Team Scientist in the department of Biomedical Sciences at the University of Wisconsin Milwaukee, engaged in understanding cellular signaling pathways in disease processes. She obtained her PhD in 2011 from Case Western Reserve University focusing the utilization of a neuronal cell model to study the oxidative stress and cell signaling pathways induced by the utilization of Levodopa therapy to treat Parkinson's Disease. Dr. Liedhegner conducted her postdoctoral studies at the Medical College of Wisconsin where she utilized mammalian models to study endocannabinoid trafficking mechanism alterations related to post-traumatic stress disorder.
Dr. Liedhegner's current research programs are focused on exploring cellular signaling mechanisms, including oxidative changes, that impact protein function and cellular health in various altered states, such as disease and trauma. The overall goal of this research is to define cellular mechanisms in culture systems and animal models that are important to disease and disorder development and progression. For this research, she employs a variety of techniques to assay whole cells including live cell imaging and immunofluorescent staining techniques, examination of signaling changes through reporter assays, and protein modifications that result in altered cellular signaling
Liedhegner, E. S., Bojar, B., Beattie, R., Cahak, C., Hristova, K., & Skwor, T. (2022, February). Similarities in virulence and extended spectrum beta-lactamase gene profiles among cefotaxime-resistant Escherichia coli wastewater and clinical isolates. Antibiotics/MDPI
Liedhegner, E. S., Vogt, C. D., Sem, D. S., Cunningham, C. W., & Hillard, C. J. (2014). Sterol carrier protein-2: Binding protein for endocannabinoids. Molecular Neurobiology
Mieyal, J. J., Gallogly, M. M., Qanungo, S., Sabens, E. A., & Shelton, M. D. (2008). Molecular mechanisms and clinical implications of reversible protein S-glutathionylation. Antioxid Redox Signal
Offer, T., Ames, B. N., Bailey, S. W., Sabens, E. A., Nozawa, M., & Ayling, J. E. (2007). 5-methyltetrahydrofolate inhibits photosensitization reactions and strand breaks in DNA. The FASEB Journal
Honors & Awards
Dean's Award for Outstanding Service (2021, May 7) UWM College of Health Sciences.
International Cannabinoid Research Symposium travel award (2012) National Institutes of Health (NIH).
International Cannabinoid Research Symposium travel award (2011) National Institutes of Health (NIH).
Postdoctoral poster presentation winner (2011) Milwaukee Chapter Society of Neuroscience.
3rd place poster presentation (2010) Research ShowCASE.
Gordon Research Conference Travel Award (2010) National Science Foundation.
Biomedical Graduate Student Symposium poster presentation winner (2009) .
Predoctoral Fellowship: NIH Institutional Metabolism Training Grant (T32 DK007319) (2009) National Institutes of Health (NIH).
Greenfield Travel Award: Best journal club presentation (2006) CWRU Department of Pharmacology.
Predoctoral Fellowship: NIH Institutional Molecular Training Grant (T32 GM008803) (2005) National Institutes of Health (NIH).