{"id":10345,"date":"2025-07-22T11:19:10","date_gmt":"2025-07-22T16:19:10","guid":{"rendered":"https:\/\/uwm.edu\/chemistry\/?page_id=10345"},"modified":"2026-03-17T15:12:44","modified_gmt":"2026-03-17T20:12:44","slug":"cook-patents","status":"publish","type":"page","link":"https:\/\/uwm.edu\/chemistry\/cook-patents\/","title":{"rendered":"Cook Patents"},"content":{"rendered":"

Patents<\/p>\n

    \n
  1. Cook, James M.; Huang, Qi; He, Xiaohui; Li, Xioayan; Yu, Jianming; Han, Dongmei; \u201cAnxiolytic Agents with Reduced Sedative and Ataxic Effects,\u201d US Patent 7,119,196 B2 (2006), 94 pages.<\/li>\n
  2. June, Harry L.; Cook, James M.; Ma, Chunrong. Methods for Reducing Alcohol Cravings in Chronic Alcoholics. U.S. Pat. Appl. Publ. (2003), 60 pp. CODEN: USXXCO US 2003176456 A1 20030918 CAN 139:241570 AN 2003:737374 CAPLUS<\/li>\n
  3. Cook, James M.; Zhou, H.; Huang, S.; Sarma, P.V.V.S.; Zhang, C. Stereospecific Anxiolytic and Anticonvulsant Agents with Reduced Muscle-Relaxant, Sedative-Hypnotic and Ataxic Effects. Provisional patent application 60\/584,143 filed June 30, 2004: PCT patent filed June 30, 2005: US patent filed June 30, 2005. Published in 2006. 2006003995 (2006), 89pp. PCT WO2006\/004945 A1. Issued 2009 US 7,618,958 (2009).<\/li>\n
  4. Cook, James M.; Han, D.; and Clayton, T.; GABAergic Agents to Treat Memory Deficits. Provisional patent filed June 30, 2005. Published in 2006. Patent No. PCT\/US 2006018721; US Patent No. 7,595,395; issued 7\/24\/2009.<\/li>\n
  5. Cook, James M.; Defoe, L.; Kabir, M. Shahjahan; Monte, A.; Rott, M.; Schwan, W., US CIP for Antiinfective Agents and Methods of Use, Filed on April 6, 2007 (US Application No. 11\/697,582); published 2007, CIP of US ser No. 163,421.<\/li>\n
  6. \u201cSelective Anticonvulsant Agents and Their Uses,\u201d J.M. Cook, R. Edwanker, C.Edwanker, S. Huang, H. Jain, F. Rivas, J. Yang, and H. Zhou, Filed provisional patent on 3\/20\/08.<\/li>\n
  7. \u201cGABAergic Receptor Subtype Selective Ligands and Their Uses,\u201d J.M. Cook, T. Clayton, H. Jain, Y. Teng, J. Yang, S. Rallapalli, Filed a provisional patent on 5\/4\/08.<\/li>\n
  8. \u201cAnxiolytic Agents with Reduced Sedative and Ataxic Effects,\u201d J.M. Cook, Q. Huang, X. He, X. Li, J. Yu, D. Han, Patent Issue No. 2003230754, 2\/29\/08. Issued 6\/26\/2007, Pat 7,265,656.<\/li>\n
  9. \u201cAnxiolytic Agents with Reduced Sedative and Ataxic Effects,\u201d J.M. Cook, Q. Huang, X. He, X. Li, J. Yu, D. Han, Patent Issue No. 255781, 3\/31\/08.<\/li>\n
  10. \u201cAnxiolytic Agents with Reduced Sedative and Ataxic Effects,\u201d J.M. Cook, Q. Huang, X. He, X. Li, J. Yu, D. Han, Patent Issue No. 10-0865410, 10\/24\/08.<\/li>\n
  11. \u201cAnxiolytic Agents with Reduced Sedative and Ataxic Effects,\u201d J.M. Cook, Q. Huang, X. He, X. Li, J. Yu, D. Han, Divisional Patent Issue No. 547480, 3\/13\/08.<\/li>\n
  12. \u201cSynthesis of Aza Beta Carbolines and Methods of Use,\u201d J. Cook, M. Van Linn and W. Yin, Provisional patent applied for June 2008. Filed electronically.<\/li>\n
  13. \u201cCysteine and Cystine Prodrugs to Treat Schizophrenia and Drug Addiction,\u201d J. Cook, D. Baker, E.M. Johnson and W. Yin, PCT\/US 09\/047099, filed April 16, 2009; WO 2009\/137251A2, International Publication date, Nov. 12, 2009.<\/li>\n
  14. \u201cCysteine and Cystine Prodrugs to Treat Schizophrenia and Drug Addiction,\u201d J. Cook, D. Baker, E.M. Johnson and W. Yin, Filed on 8\/11\/08. Application number 12189516. Published 08\/13\/2009; PCT WO 2009\/100431 A1.<\/li>\n
  15. \u201cSelective Agents for Pain Suppression\u201d, J.M.Cook, S.Huang, R.Edwankar, O. Namjoshi, Z. Wang, US Patent Pub# US 2010\/0317619A1, Pub. Date Dec. 16, 2010.<\/li>\n
  16. \u201cGabaergic Receptor Subtype Selective Ligands and their Uses,\u201d Cook, J. M., S. Rallapalli, T. Clayton, H. Jain, J. Yang, Teng, Y., provisional patent filed on 4\/28\/2011, Application # 6147899.<\/li>\n
  17. \u201cCysteine and Cystine Prodrugs to Treat Schizophrenia and Drug Addiction,\u201d J. Cook, D. Baker, E.M. Johnson and W. Yin, US Patent Issued No: US 7,829,709 B1, Nov. 9th 2010.<\/li>\n
  18. \u201cAza-Beta- Carbolines and Method of Using Same,\u201d Cook, James; Van Linn, Michael; Yin, Wenyuan, filed US\/22.05.08\/USP 55334; Application No\/Patent No 09751673.6021\/7 PCT\/US2009045014.<\/li>\n
  19. \u201cBroad Spectrum-Gram \u2013Positive \u2013Antimicrobials and Anthemintics with Efficacy Against DrugResistant Strains and Mycobacterium Species,\u201d CIP Application filed 12\/20\/2010, Cook, J.; Monte, A.; Schwan, W.; Kabir, S.; Rott, Marc; Miskowski, J., Serial # 12\/973, 078 (2010).<\/li>\n
  20. \u201cBroad Spectrum-Gram-Positive-Antimicrobials with Efficacy Against Drug-Resistant Strains and Mycobacterium Species,\u201d Cook, J.; Monte, A.; Schwan, W.; Rott, M.; Kabir, S., Provisional filed, 1\/15\/2010, Serial # 61\/295,384 (2010).<\/li>\n
  21. \u201cStereospecific Synthesis of Acrylate Ethers and Amines for Industrial and Medicinal Applications,\u201d Kabir, M.; Cook, J.M.; Monte, A.; Rott, M.; Schwan, W.; Witzigmann, C.; Namjoshi, O.; Babu, V.V.N.Phani; Verma, R. Provisional filed 14 March (2012), Serial # 61\/610,574.<\/li>\n
  22. \u201cCysteine and Cystine Prodrugs to Treat Schizophrenia and Drug Cravings,: Cook, J.; Baker, D.; Johnson, Edward (Merle); Yin, Wenyuan, US Utility Patent, Serial# 12\/367,867, Filed 2\/9\/2009, Issued 5\/8\/2012.<\/li>\n
  23. \u201cCysteine and Cystine Prodrugs to Treat Schizophrenia and Reduce Drug Cravings,: Cook, J.; Baker, D.; Johnson, E.; Yin, W., US Patent, Divisonal, Serial number 13\/465,383; Filed 5\/7\/2012.<\/li>\n
  24. \u201cSelective Agents for Pain Suppression\u201d, J. Cook, S. Huang, R. Edwankar, O. Namjoshi, Z. Wang, US Patent, Published October 27, 2012, Patent number US2010\/0261711 A1. Issued September 16, 2014, US8,835,424B2.<\/li>\n
  25. \u201cAza-Beta Carbolines and Methods of Using Same\u201d, J. Cook, M. VanLinn, W. Yin, US Patent number: US 8,268,854B2, September 18, 2012.<\/li>\n
  26. \u201cCysteine and Cystine Prodrugs to Treat Schizophrenia and Reduce Drug Cravings\u201d, J. Cook, D. Baker, W.Yin, E.M.Johnson II, Pub. No. US2012\/0220596A1, Pub. Date: August 30, 2012.<\/li>\n
  27. \u201cDevelopment of GABA (A) Agonists to Control Airway Hyperresponsiveness and Inflamation in Asthma\u201d, D. Stafford, J. Cook, A. Arnold, C. Emala, Provisional Patent Filed September 21, 2012, Application number 61703902, confirmation number 2765, RAM number 9468. Published 2014.<\/li>\n
  28. \u201cCysteine and Cystine Bioisosteres to Treat Schizophrenia and Reduce Drug Cravings\u201d, J. Cook, D. Baker, E. M. Johnson Jr., W. Yin, European Patent Council, 09707256.5, filed 6\/9\/2010.<\/li>\n
  29. \u201cCysteine and Cystine Bioisosteres to Treat Schizophrenia and Reduce Drug Cravings\u201d, J. Cook, D. Baker, E. M. Johnson Jr., W. Yin, European Patent Council, US, 9743238.9, filed 9\/16\/2010.<\/li>\n
  30. \u201cCysteine and Cystine Bioisosteres to Treat Schizophrenia and Reduce Drug Cravings\u201d, J. Cook, D. Baker, E. M. Johnson Jr., W. Yin, 13\/465,383, filed 5\/7\/2012<\/li>\n
  31. \u201cGABAergic Receptor Subtype Selective Ligands and Their Uses, \u201cCook, J. M., Clayton, T., Jain, H.D., Rallapalli, S. K., Johnson, Y. T.,Yang, J.,Poe, M.M., Namjoshi, O. A., Wang, Z. Patent publication no US 2012\/0295892 A1, Published November 22nd, 2012; Notice of Allowance, 13\/458, 168 (2015).<\/li>\n
  32. \u201cCysteine Prodrugs to Treat Schizophrenia and Drug Addiction\u201d, J. Cook, D. Baker, W.Yin, E.M.Johnson II, Pub. No. US 8,435,997 B2, Pub. Date: May 7, 2013.<\/li>\n
  33. \u201cDesign and Synthesis of Acrylate Esters with Activity Against Bacteria and Mycobacteria, Including M. Tuberculosis and Methicillin Resistant S. Aurerus (MRSA)., M. Kabir, J.M. Cook, A. Monte, M. Rott, W. Schwan, C. Witzigman, O. Namjoshi, V.V.N. Phani Tiruveedhula, R. Verma, Provisional Patent Applied for 4\/10\/13. Serial # 61\/810, 487.<\/li>\n
  34. \u201cNovel GABA(A) Agonists and Methods of Using to Control Airway Hyperresponsiveness and Inflamation in Asthma,\u201d D. Stafford, J.M. Cook, A. Arnold, C. Emala, G. Gallos, M.R. Stephen, PCT patent filed 9\/20\/13; PCT\/US13\/60859. Published March 27, 2014; WO2014\/047413A1.<\/li>\n
  35. \u201cCysteine And Cystine Bioisosteres to Treat Schizophrenia and Reduce Drug Cravings,\u201d Cook, J.; Baker, D.; Johnson II, E.M.; Yin, W.; Verma, R., US Application No 14\/148959, CIP Application, Pub. No.: US2014\/01554410A1, June 5, 2014; Notice of Allowance, 13\/465,383.<\/li>\n
  36. Compounds for the Treatment of Gram-Positive Infections Including Resistant Strains of Staphylococcus aureus,\u201d Cook, J.; Witzigman, C.; Tiruveedhula, V.; Monte, A.; Schwan, W.; Rott, M.; provisional patent submitted 4\/4\/2014.<\/li>\n
  37. \u201cCysteine and Cystine Prodrugs to Treat Schizophrenia and Reduce Drug Cravings,\u201d Cook, J.M; Baker, D.; Yin, W.; Johnson II, E.M. Divisional filed Feb. 20th, 2015, Patent No. 14\/627,379.<\/li>\n
  38. \u201cCysteine and Cystine Prodrugs to Treat Schizophrenia and Reduce Drug Cravings,\u201d Cook, J.M; Baker, D.; Yin, W.; Johnson II, E.M. Japenese Patent, P16851, 885-911 (2014.12.5) 2014.<\/li>\n
  39. \u201cGabaergic Ligands and Their Uses,\u201d Cook, J.; Poe, M.; Methuku, K.; Li, G.; Provisional Patent filed March 20th, 2015.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

    Patents Cook, James M.; Huang, Qi; He, Xiaohui; Li, Xioayan; Yu, Jianming; Han, Dongmei; \u201cAnxiolytic Agents with Reduced Sedative and Ataxic Effects,\u201d US Patent 7,119,196 B2 (2006), 94 pages. June, Harry L.; Cook, James M.; Ma, Chunrong. Methods for Reducing …<\/p>\n","protected":false},"author":382,"featured_media":0,"parent":0,"menu_order":13,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":"","uwm_wg_additional_authors":[]},"class_list":["post-10345","page","type-page","status-publish","hentry"],"yoast_head":"\nChemistry & Biochemistry<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/uwm.edu\/chemistry\/cook-patents\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cook Patents\" \/>\n<meta property=\"og:description\" content=\"Patents Cook, James M.; Huang, Qi; He, Xiaohui; Li, Xioayan; Yu, Jianming; Han, Dongmei; \u201cAnxiolytic Agents with Reduced Sedative and Ataxic Effects,\u201d US Patent 7,119,196 B2 (2006), 94 pages. 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