Mutchie, Tania

Expected Year of Graduation: 2021
Research Lab: Arnold Group
Major Area of Focus: Organic Chemistry, Medicinal Chemistry

Thesis:

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Previously Attended:

Drake University (2011-2015)

Why I like Chemistry:

Studying chemistry gives me a greater understanding of the world we live in and there is always something new to learn.

Why I chose the Chemistry and Biochemistry Program at UW-Milwaukee:

UWM has intelligent faculty members and good resources that are able to help me further my career as a chemist. I'm also from the Milwaukee area so it is nice to be near my family.

Favorite things to do in Milwaukee:

I like to spend as much time outdoors as possible; camping, kayaking, and going to the beach are a few of my favorite activities.

Research Goal:

To develop and characterize compounds that selectively interact with the vitamin D receptor and are traceable both in vitro and in vivo.

Publications

Mutchie, T.R., Webb, D.A., Di Milo, E.S., Arnold, L.A. Ligand Design for the Vitamin D Receptor. Nuclear Receptors, Badr M.Z. Ed. 2020 in press.

Yu, O. B.; Mutchie, T. R.; Di Milo, E. S.; Arnold, L. A., Synthesis and biological evaluation of calcioic acid. Steroids 2020, 154, 108536.

Mutchie, T. R.; Yu, O. B.; Di Milo, E. S.; Arnold, L. A., Alternative binding sites at the vitamin D receptor and their ligands. Molecular and cellular endocrinology 2019, 485, 1-8.

Poster Presentations

Development of small-molecule-based probes for the vitamin D receptor, ACS National Meeting & Expo, Poster Presentation, August 2020. https://doi.org/10.1021/scimeetings.0c06774

Development of small-molecule-based probes for the vitamin D receptor, ACS National Meeting & Expo, Poster Presentation, March 2020. https://doi.org/10.1021/scimeetings.0c02057

Synthesis of novel compounds to study expression and localization of the vitamin D receptor, UWM Department of Chemistry & Biochemistry Research Symposium, Poster Presentation, April 2019.

Synthesis of novel compounds to study expression and localization of the vitamin D receptor, Milwaukee Analytical Chemistry Conference (MACC), Poster Presentation, January 2019.

Synthesis of novel compounds to study expression and localization of the vitamin D receptor, UWM Department of Chemistry & Biochemistry Research Symposium, Poster Presentation, May 2018.

Synthesis of novel compounds to study expression and localization of the vitamin D receptor, UWM Department of Chemistry & Biochemistry Research Symposium, Poster Presentation, May 2017.

Awards and Fellowships

MilliporeSigma Summer Graduate Research Fellowship (2020)

Sosnovsky Award for Excellence in Graduate Research (2020)

UWM Graduate Student Excellence Fellowship (GSEF) (2020)

Teaching Assistant Award, Discussion (2019)