Han, Lanlan

PhD

Chemistry & Biochemistry

Year of Graduation: 2017
Research Lab: Prof. Nicolas Silvaggi
Major Area of Focus: Biochemistry
Minor Area of Focus: Organic Chemistry

Dissertation: Structure-Function Relationships in Bacterial Regulatory Proteins and an Enzyme Involved in Antibiotic Biosynthesis

Publications

Zhu Y, Han L, Hefferon KL, Sivaggi NR, Wilson DB, McBride MJ. Periplasmic Cytophaga hutchinsonii endoglucanases are required for use of crystalline cellulose as sole carbon and energy source. Applied and Environmental Microbiology. 2016, 82 (15): 4835-4845

Han L, Schwabacher AW, Moran GR, Silvaggi NR.Streptomyces wadayamensis MppP is a PLP-Dependent L-Arginine α-deaminase, γ-Hydroxylase in the Enduracididine Biosynthetic Pathway. Biochemistry. 2015, 54: 7029−7040

Maule AF, Wright DP, Weiner JJ, Han L, Peterson FC, Volkman BF, Silvaggi NS, Ulijasz AT. The aspartate-less receiver (ALR) domains: distribution, structure and function. PLOS Pathogens. 2015, 11(4): e1004795

Guthrie ML, Sidhu PS, Hill EK, Horan TC, Nandhikonda P, Teske KA, Yuan NY, Sidorko M, Rodali R, Cook JM, Han L, Silvaggi NR, Bikle DD, Moore RG, Singh RK, Arnold LA. Antitumor Activity of 3-Indolylmethanamines 31B and PS121912. Anticancer Research. 2015, 35(11): 6001-6007

Teske K, Nandhikonda P, Bogart JW, Feleke B, Sidhu P, Yuan N, Preston J, Goy R, Han L, Silvaggi NR, Singh RK, Bikle DD, Cook JM, Arnold LA. Identification of VDR antagonists among nuclear receptor ligands using virtual screening. Nuclear Receptor Research. 2014, 1. pii: 101076

Sidhu PS, Teske K, Feleke B, Yuan NY, Guthrie ML, Fernstrum GB, Vyas ND, Han L, Preston J, Bogart JW, Silvaggi NR, Cook JM, Singh RK, Bikle DD, Arnold LA. Anticancer activity of VDR-coregulator inhibitor PS121912. Cancer Chemotherapy Pharmacology. 2014, 74(4): 787-798

Zhang X, Hu S, Du X, Li T, Han L, Kong J. Heterologous expression of carcinoembryonic antigen in Lactococcus lactis via LcsB-mediated surface displaying system for oral vaccine development. Journal of Microbiology, Immunology, and Infection. 2016, 49(6): 851-858

Hu S, Kong J, Sun Z, Han L, Kong W, Yang P. Heterologous Protein Display on the Cell Surface of Lactic Acid Bacteria Mediated by the S-Layer Protein. Microbial Cell Factories 2011, DOI: 10.1186/1475-2859-10-86