Mass Spectrometry Laboratory

Shimadzu instruments

Assistant professor / director of the shimadzu laboratory Shama Mirza
E-mail mirza@uwm.edu
Rooms KEN 2076
Phone (414) 229-3658

The Mass Spectrometry Laboratory at the Department of Chemistry and Biochemistry provides a variety of mass spectrometry analysis qualitatively or/and quantitatively. The facility currently houses the following mass spectrometry systems

  1. Shimadzu GCMS-QP2010 Ultra equipped with EI, CI, or nCI
  2. Shimadzu LCMS-2020 equipped with ESI and APCI dual ion source
  3. Shimadzu LCMS-8040 equipped with ESI and APCI dual ion source
  4. Shimadzu LCMS-IT-TOF equipped with ESI or APCI
  5. Shimadzu MALDI-7090 equipped with MALDI

Using the ultra-fast, ultra-sensitive research-quality Shimadzu GCMS-QP2010 Ultra equipped with EI, CI, or nCI, the lab is able to analyze trace compounds that contribute to environmental pollution, affect human health as well as novel compounds related to research. Employing a Shimadzu LCMS-2020 as an LC detector can effectively reduce the limitations of LC analysis. The “LCMS-2020” single quadrupole ultra-fast LC/MS is capable of providing more data points and faster scans and allowing it to handle the fastest small-particle and high efficiency columns for the analysis of compound identifications. By using Shimadzu LCMS-8040 equipped with ESI and APCI dual ion source, the lab can provide the analysis for definitive identification and reproducible quantification of trace level analyses in complex samples for a variety of applications such as pharmacokinetics in pharma/CRO, food environmental, forensic/toxicology, and newborn screening. Shimadzu LCMS-IT-TOF is a hybrid mass spectrometer which possesses both the MSn ability of an ion trap and the excellent resolution and mass accuracy of a TOF. By using the LCMS-IT-TOF, the lab provides the service for the prediction of molecular elemental composition and structural analysis.  With the state of art MALDI-7090™ MALDI TOF-TOF mass spectrometer targeted for proteomics and tissue imaging research, the lab provides the ultimate capabilities for identification and structural characterization of biomolecules.

The mass spectrometry laboratory also provides training for faculty, staff and students to utilize the mass spectrometers to perform mass analysis for mass spectrometry analysis. Please feel free to consult us for your analysis.

In addition to the mass spectrometry core services provided by Department of Chemistry and Biochemistry Mass Spectrometry Laboratory, the laboratory also conducts collaborative research programs with investigators from the Departments on the UWM campus.  In June 2014, the laboratory was also named as Shimadzu Laboratory for Advanced and Applied Analytical Chemistry.