{"id":7990,"date":"2024-09-10T14:49:11","date_gmt":"2024-09-10T19:49:11","guid":{"rendered":"https:\/\/uwm.edu\/biology\/?post_type=tribe_events&#038;p=7990"},"modified":"2024-09-10T14:49:11","modified_gmt":"2024-09-10T19:49:11","slug":"biological-sciences-colloquium-dr-claire-de-la-cova","status":"publish","type":"tribe_events","link":"https:\/\/uwm.edu\/biology\/event\/biological-sciences-colloquium-dr-claire-de-la-cova\/","title":{"rendered":"Biological Sciences Colloquium: Dr. Claire de la Cova"},"content":{"rendered":"<p>Dr. Claire de la Cova, assistant professor of biological sciences at UWM, will present a talk about her work entitled, &#8220;The very elegant patient: How the worm <em>C. elegans<\/em> provides insights into Raf signaling in disease.&#8221;<\/p>\n<p>The summary is as follows:<\/p>\n<p>&#8220;Raf protein kinases act as Ras-GTP sensing components of the ERK signal transduction pathway in animal cells, influencing cell proliferation, differentiation, and survival. In humans, somatic and germline mutations in the genes <em>BRAF<\/em> and <em>RAF1<\/em> are associated with cancers and developmental disorders. Our approach to investigate Raf signaling uses the roundworm <em>Caenorhabditis elegans<\/em>, which has a single Raf ortholog termed LIN-45. I will share our insights into how Raf kinase activity, protein localization, and degradation are controlled in animals, and how these mechanisms may impact human diseases.&#8221;<\/p>\n<p>The presentation will begin at 4:00 PM in Lapham Hall N101, preceded by an informal reception from 3:45 &#8211; 4:00 PM.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dr. Claire de la Cova, assistant professor of biological sciences at UWM, will present a talk about her work entitled, &#8220;The very elegant patient: How the worm C. elegans provides insights into Raf signaling in disease.&#8221; The summary is as &hellip;<\/p>\n","protected":false},"author":37839,"featured_media":7991,"template":"","meta":{"_acf_changed":false,"_tribe_events_status":"","_tribe_events_status_reason":"","_tribe_events_is_hybrid":"","_tribe_events_is_virtual":"","_tribe_events_virtual_video_source":"","_tribe_events_virtual_embed_video":"","_tribe_events_virtual_linked_button_text":"","_tribe_events_virtual_linked_button":"","_tribe_events_virtual_show_embed_at":"","_tribe_events_virtual_show_embed_to":[],"_tribe_events_virtual_show_on_event":"","_tribe_events_virtual_show_on_views":"","_tribe_events_virtual_url":"","footnotes":"","uwm_wg_additional_authors":[]},"tags":[],"tribe_events_cat":[36],"class_list":["post-7990","tribe_events","type-tribe_events","status-publish","has-post-thumbnail","hentry","tribe_events_cat-colloquia","cat_colloquia"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.2 (Yoast SEO v27.2) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Biological Sciences<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/uwm.edu\/biology\/event\/biological-sciences-colloquium-dr-claire-de-la-cova\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Biological Sciences Colloquium: Dr. Claire de la Cova\" \/>\n<meta property=\"og:description\" content=\"Dr. Claire de la Cova, assistant professor of biological sciences at UWM, will present a talk about her work entitled, &#8220;The very elegant patient: How the worm C. elegans provides insights into Raf signaling in disease.&#8221; The summary is as &hellip;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/uwm.edu\/biology\/event\/biological-sciences-colloquium-dr-claire-de-la-cova\/\" \/>\n<meta property=\"og:site_name\" content=\"Biological Sciences\" \/>\n<meta property=\"og:image\" content=\"https:\/\/uwm.edu\/biology\/wp-content\/uploads\/sites\/21\/2024\/09\/2024_September_13_delaCova.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1280\" \/>\n\t<meta property=\"og:image:height\" content=\"720\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/uwm.edu\/biology\/event\/biological-sciences-colloquium-dr-claire-de-la-cova\/\",\"url\":\"https:\/\/uwm.edu\/biology\/event\/biological-sciences-colloquium-dr-claire-de-la-cova\/\",\"name\":\"Biological Sciences Colloquium: Dr. Claire de la Cova - Biological Sciences\",\"isPartOf\":{\"@id\":\"https:\/\/uwm.edu\/biology\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/uwm.edu\/biology\/event\/biological-sciences-colloquium-dr-claire-de-la-cova\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/uwm.edu\/biology\/event\/biological-sciences-colloquium-dr-claire-de-la-cova\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/uwm.edu\/biology\/wp-content\/uploads\/sites\/21\/2024\/09\/2024_September_13_delaCova.jpg\",\"datePublished\":\"2024-09-10T19:49:11+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/uwm.edu\/biology\/event\/biological-sciences-colloquium-dr-claire-de-la-cova\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/uwm.edu\/biology\/event\/biological-sciences-colloquium-dr-claire-de-la-cova\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/uwm.edu\/biology\/event\/biological-sciences-colloquium-dr-claire-de-la-cova\/#primaryimage\",\"url\":\"https:\/\/uwm.edu\/biology\/wp-content\/uploads\/sites\/21\/2024\/09\/2024_September_13_delaCova.jpg\",\"contentUrl\":\"https:\/\/uwm.edu\/biology\/wp-content\/uploads\/sites\/21\/2024\/09\/2024_September_13_delaCova.jpg\",\"width\":1280,\"height\":720,\"caption\":\"2024 September 13 delaCova\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/uwm.edu\/biology\/event\/biological-sciences-colloquium-dr-claire-de-la-cova\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/uwm.edu\/biology\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Events\",\"item\":\"https:\/\/uwm.edu\/biology\/upcoming\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Colloquia\",\"item\":\"https:\/\/uwm.edu\/biology\/events\/category\/colloquia\/\"},{\"@type\":\"ListItem\",\"position\":4,\"name\":\"Biological Sciences Colloquium: Dr. Claire de la Cova\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/uwm.edu\/biology\/#website\",\"url\":\"https:\/\/uwm.edu\/biology\/\",\"name\":\"Biological Sciences\",\"description\":\"UW-Milwaukee\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/uwm.edu\/biology\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO Premium plugin. -->","yoast_head_json":{"title":"Biological Sciences","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/uwm.edu\/biology\/event\/biological-sciences-colloquium-dr-claire-de-la-cova\/","og_locale":"en_US","og_type":"article","og_title":"Biological Sciences Colloquium: Dr. Claire de la Cova","og_description":"Dr. Claire de la Cova, assistant professor of biological sciences at UWM, will present a talk about her work entitled, &#8220;The very elegant patient: How the worm C. elegans provides insights into Raf signaling in disease.&#8221; The summary is as &hellip;","og_url":"https:\/\/uwm.edu\/biology\/event\/biological-sciences-colloquium-dr-claire-de-la-cova\/","og_site_name":"Biological Sciences","og_image":[{"width":1280,"height":720,"url":"https:\/\/uwm.edu\/biology\/wp-content\/uploads\/sites\/21\/2024\/09\/2024_September_13_delaCova.jpg","type":"image\/jpeg"}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/uwm.edu\/biology\/event\/biological-sciences-colloquium-dr-claire-de-la-cova\/","url":"https:\/\/uwm.edu\/biology\/event\/biological-sciences-colloquium-dr-claire-de-la-cova\/","name":"Biological Sciences Colloquium: Dr. Claire de la Cova - Biological Sciences","isPartOf":{"@id":"https:\/\/uwm.edu\/biology\/#website"},"primaryImageOfPage":{"@id":"https:\/\/uwm.edu\/biology\/event\/biological-sciences-colloquium-dr-claire-de-la-cova\/#primaryimage"},"image":{"@id":"https:\/\/uwm.edu\/biology\/event\/biological-sciences-colloquium-dr-claire-de-la-cova\/#primaryimage"},"thumbnailUrl":"https:\/\/uwm.edu\/biology\/wp-content\/uploads\/sites\/21\/2024\/09\/2024_September_13_delaCova.jpg","datePublished":"2024-09-10T19:49:11+00:00","breadcrumb":{"@id":"https:\/\/uwm.edu\/biology\/event\/biological-sciences-colloquium-dr-claire-de-la-cova\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/uwm.edu\/biology\/event\/biological-sciences-colloquium-dr-claire-de-la-cova\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/uwm.edu\/biology\/event\/biological-sciences-colloquium-dr-claire-de-la-cova\/#primaryimage","url":"https:\/\/uwm.edu\/biology\/wp-content\/uploads\/sites\/21\/2024\/09\/2024_September_13_delaCova.jpg","contentUrl":"https:\/\/uwm.edu\/biology\/wp-content\/uploads\/sites\/21\/2024\/09\/2024_September_13_delaCova.jpg","width":1280,"height":720,"caption":"2024 September 13 delaCova"},{"@type":"BreadcrumbList","@id":"https:\/\/uwm.edu\/biology\/event\/biological-sciences-colloquium-dr-claire-de-la-cova\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/uwm.edu\/biology\/"},{"@type":"ListItem","position":2,"name":"Events","item":"https:\/\/uwm.edu\/biology\/upcoming\/"},{"@type":"ListItem","position":3,"name":"Colloquia","item":"https:\/\/uwm.edu\/biology\/events\/category\/colloquia\/"},{"@type":"ListItem","position":4,"name":"Biological Sciences Colloquium: Dr. Claire de la Cova"}]},{"@type":"WebSite","@id":"https:\/\/uwm.edu\/biology\/#website","url":"https:\/\/uwm.edu\/biology\/","name":"Biological Sciences","description":"UW-Milwaukee","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/uwm.edu\/biology\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"acf":[],"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/uwm.edu\/biology\/wp-json\/wp\/v2\/tribe_events\/7990","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/uwm.edu\/biology\/wp-json\/wp\/v2\/tribe_events"}],"about":[{"href":"https:\/\/uwm.edu\/biology\/wp-json\/wp\/v2\/types\/tribe_events"}],"author":[{"embeddable":true,"href":"https:\/\/uwm.edu\/biology\/wp-json\/wp\/v2\/users\/37839"}],"version-history":[{"count":1,"href":"https:\/\/uwm.edu\/biology\/wp-json\/wp\/v2\/tribe_events\/7990\/revisions"}],"predecessor-version":[{"id":7992,"href":"https:\/\/uwm.edu\/biology\/wp-json\/wp\/v2\/tribe_events\/7990\/revisions\/7992"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/uwm.edu\/biology\/wp-json\/wp\/v2\/media\/7991"}],"wp:attachment":[{"href":"https:\/\/uwm.edu\/biology\/wp-json\/wp\/v2\/media?parent=7990"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/uwm.edu\/biology\/wp-json\/wp\/v2\/tags?post=7990"},{"taxonomy":"tribe_events_cat","embeddable":true,"href":"https:\/\/uwm.edu\/biology\/wp-json\/wp\/v2\/tribe_events_cat?post=7990"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}