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X-WR-CALNAME:Biological Sciences
X-ORIGINAL-URL:https://uwm.edu/biology
X-WR-CALDESC:Events for Biological Sciences
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DTSTART;TZID=America/Chicago:20240405T160000
DTEND;TZID=America/Chicago:20240405T170000
DTSTAMP:20240403T193031Z
CREATED:20240403T193031Z
LAST-MODIFIED:20240403T193031Z
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SUMMARY:Biological Sciences Colloquium:  Dr. Jean-Pierre Saint-Jeannet
DESCRIPTION:Dr. Jean-Pierre Saint-Jeannet\, New York University\, will present a talk about his work entitled\, “Understanding the Role of The Spliceosome in Craniofacial Syndromes: A Tale of Frogs and Embryonic Stem Cells.” \nThe Abstract is as Follows: \nSynopsis: Nager syndrome is a rare craniofacial and limb disorder characterized by midface retrusion\, micrognathia\, absent thumbs\, and radial hypoplasia. This disorder results from mutations in SF3B4 gene\, which encodes a core component of the spliceosome. While the spliceosome is present and functions in all cells of the body to remove introns and join exons from transcribed pre-mRNA\, many spliceosomopathies – including Nager syndrome – are often cell/tissue-specific in their pathology. In Nager syndrome patients it is the neural crest-derived craniofacial skeletal structures that are primarily affected. To understand the pathomechanism underlying this condition\, we have developed two models of Nager syndrome by knocking down SF3B4 in Xenopus tropicalis and in human embryonic stem cells. We will present and discuss some of our findings. \n 
URL:https://uwm.edu/biology/event/biological-sciences-colloquium-dr-jean-pierre-saint-jeannet/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
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BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20240412T093000
DTEND;TZID=America/Chicago:20240412T150000
DTSTAMP:20240410T185446Z
CREATED:20240410T185042Z
LAST-MODIFIED:20240410T185446Z
UID:10001346-1712914200-1712934000@uwm.edu
SUMMARY:Spring 2024 Biological Sciences Research Symposium
DESCRIPTION:The Graduate Organization of Biological Sciences (GOBS)\, in conjunction with the Department of Biological Sciences\, presents the 2024 Biological Sciences Research Symposium. The symposium is designed to showcase our outstanding undergraduate and graduate students and their research in the department. Advance registration required. \nView this year’s program by clicking here!
URL:https://uwm.edu/biology/event/spring-2024-biological-sciences-research-symposium/
LOCATION:UWM Student Union Ballroom\, 2200 E. Kenwood Blvd\, Milwaukee\, WI\, 53201
CATEGORIES:Department
ATTACH;FMTTYPE=image/png:https://uwm.edu/biology/wp-content/uploads/sites/21/2023/09/download-2.png
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BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20240412T160000
DTEND;TZID=America/Chicago:20240412T170000
DTSTAMP:20240409T190253Z
CREATED:20240409T190253Z
LAST-MODIFIED:20240409T190253Z
UID:10001345-1712937600-1712941200@uwm.edu
SUMMARY:Biological Sciences Colloquium: Laura Rolfs
DESCRIPTION:Laura Rolfs will present a talk about his/her/their work entitled\, “The role of non-muscle myosins in zebrafish development and MYH9-related disease” \nThe Abstract is as Follows: \nMYH genes encode highly conserved actin-based motor proteins\, non-muscle myosins (NMIIs)\, which have essential roles in cell division\, cell migration\, and cell shape changes. Zebrafish have two myh9 genes (myh9a and myh9b) which encode for the NMIIA protein\, along with myh10 and myh14\, which encode for NMIIB and NMIIC\, respectively. To understand the role of myh genes in development\, we obtained a null mutant for the myh9a gene and generated null mutants for the myh9b and myh10 genes using CRISPR/Cas genome editing. myh14 was not examined due to the low sequence homology. Through our studies we identified myh9b\, not myh9a or myh10\, as the critical myh gene required for normal zebrafish development and morphogenesis. Consistent with this finding\, myh9a and myh10 homozygous mutants are viable through adulthood with no visible phenotypes. However\, myh9b homozygous mutants are semi-lethal and develop pericardial edema between 48 and 96 hours post fertilization\, a phenotype consistent with kidney dysfunction. This phenotype reverses shortly after onset\, leading us to hypothesize that there is redundancy or compensation by other myh genes and proteins in these mutants. This is supported by the finding that double mutants display more severe phenotypes earlier in development than single mutants. In the human population there are five clinical disorders resulting from mutations in the MYH9 gene that are classified as MYH9-related disease (MYH9-RD)\, with many patients developing kidney dysfunction. Examination of larval myh9b homozygous mutant kidney structure revealed severe defects including podocyte foot process effacement\, increased slit diaphragm size\, and protein precipitate in Bowman’s space. These results suggest that myh9b mutants can be used as a model to study the development and progression of MYH9-RD. Current experiments are further investigating glomerular function and the cell type specific role for myh9b in development.
URL:https://uwm.edu/biology/event/biological-sciences-colloquium-laura-rolfs/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
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BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20240419T160000
DTEND;TZID=America/Chicago:20240419T170000
DTSTAMP:20240416T135054Z
CREATED:20240416T135054Z
LAST-MODIFIED:20240416T135054Z
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SUMMARY:Biological Sciences Colloquium: Shanice Piango
DESCRIPTION:Shanice Piango\, UWM graduate student\, will present a talk about her work entitled\, “Germplasm Conservation Strategies for Understanding Fertility in Giant Kelp (Macrocystis Pyrifera)” \nThe Abstract is as Follows: \nMy research explores the application of germplasm conservation strategies in seaweed\, focusing on the fertility of stored gametophytes\, microbiome interactions with antibiotic treatment\, and germplasm longevity. As seaweed ecosystems face threats from climate change along with the rapidly growing seaweed aquaculture industry\, germplasm conservation emerges as a key strategy for preserving biodiversity and supporting aquaculture. Germplasm conservation is instrumental in sustaining biodiversity and ecosystem services\, particularly for improving the aquaculture of Macrocystis pyrifera. Our investigation delves into the challenges of declining gametophyte fertility over time\, investigating gene expression differences between sexes and what genes play major roles in successful reproduction\, examining the role of microbiome interactions and antibiotics in germplasm health\, and assesses strategies to enhance the longevity and viability of stored seaweed germplasm. \nThe presentation will begin at 4:00PM in Lapham Hall N101\, preceded by an informal reception from 3:45-4:00PM.
URL:https://uwm.edu/biology/event/biological-sciences-colloquium-shanice-piango/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
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BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20240426T160000
DTEND;TZID=America/Chicago:20240426T170000
DTSTAMP:20240423T132525Z
CREATED:20240423T132525Z
LAST-MODIFIED:20240423T132525Z
UID:10001348-1714147200-1714150800@uwm.edu
SUMMARY:Biological Sciences Colloquium: Dr. Devanshi Khokhani
DESCRIPTION:Dr. Devanshi Khokhani will present a talk about her work entitled\, “Harnessing Rhizosphere Microbes to Foster Plant Health.” \nThe abstract is as follows: \nRhizosphere\, a narrow zone at the soil-root interface\, is an untapped resource for discovering beneficial microbes that can fight plant pathogens and increase crop yields in a sustainable way. Uncontrolled use of conventional agrochemicals such as pesticides and fertilizers used to manage crop yields affects soil health and eventually plant health. We study rhizosphere microbes of corn to develop robust biological control agents and biofertilizers. Through in vitro and growth chamber assays\, we tested the antagonistic activity of a bacterial synthetic community (SynComs)\, against some of the prominent corn root rot pathogens. We found that the SynCom significantly inhibited the growth of an oomycete and some fungal pathogens and now we are in the process of identifying inhibitory microbial products secreted by the community. Next\, to reduce our dependence on synthetic nitrogen fertilizers\, we sought to study cross-kingdom interactions of a fungal root endosymbiont\, called mycorrhizal fungi\, and nitrogen-fixing bacteria. Co-inoculation of the fungus with a robust nitrogen fixer increased the colonization of corn roots and improved the transfer of fixed N to corn\, with 16 to 25 % of nitrogen-derived from the atmosphere. These findings suggest that mycorrhizal fungi mediate the transfer of fixed nitrogen to plants and that the nitrogen-fixer also acts as a helper bacterium by enhancing the colonization of corn roots. Overall\, our results highlight the importance and potential of rhizosphere microbes towards sustainable management of plant health. \nThe presentation will begin at 4:00 PM in Lapham Hall N101\, preceded by an informal reception from 3:45 – 4:00 PM.
URL:https://uwm.edu/biology/event/biological-sciences-colloquium-dr-devanshi-khokhani/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
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