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BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20240202T160000
DTEND;TZID=America/Chicago:20240202T170000
DTSTAMP:20260516T085506
CREATED:20240125T222241Z
LAST-MODIFIED:20240126T150935Z
UID:10001336-1706889600-1706893200@uwm.edu
SUMMARY:Biological Sciences Colloquium:  Dr. Alita Burmeister
DESCRIPTION:Title: Trade-offs and Trade-ups in Bacteria-Phage Coevolution \nAbstract: Evolutionary trade-offs are thought to be a fundamental factor constraining adaptation in natural populations. Trade-offs have also been leveraged in the treatment of bacterial infections through selection by phage at the expense of antibiotic resistance. However\, it is currently unknown how widespread and reliable such trade-offs may be. My group is using a combination of experimental evolution and molecular genetics to uncover when such tradeoffs may be in effect. We have discovered the potential for trade-offs between phage resistance and antibiotic resistance mediated by the lytic Escherichia coli phage U136B. We found that phage U136B adsorbs to TolC\, which is an outer membrane protein component of a multidrug efflux pump. Using experimental evolution\, we show that loss or modification of the tolC gene is a common evolutionary response to selection by phage U136B\, whereby some phage resistant mutants have reduced antibiotic resistance. However\, we also found that this trade-off strongly depended on the antibiotic\, type of selection experiment\, and the specific host resistance mutation. In some cases\, bacteria even evaded the trade-off such that phage-resistant mutants had the same or greater antibiotic resistance. In new work\, we are investigating alternative mutational pathways to phage resistance and the impact of host resistance on phage coevolution. Overall\, our results suggest that phage resistance may sometimes\, but not always\, help maintain antibiotic sensitivity in bacterial populations.
URL:https://uwm.edu/biology/event/biological-sciences-colloquium-dr-alita-burmeister/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
X-TRIBE-STATUS:
GEO:43.0757204;-87.8840564
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=Lapham Hall N101 3209 N Maryland Ave Milwaukee WI 53211 United States;X-APPLE-RADIUS=500;X-TITLE=3209 N Maryland Ave:geo:-87.8840564,43.0757204
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20240216T160000
DTEND;TZID=America/Chicago:20240216T170000
DTSTAMP:20260516T085506
CREATED:20240208T182347Z
LAST-MODIFIED:20240208T182913Z
UID:10001338-1708099200-1708102800@uwm.edu
SUMMARY:Biological Sciences Colloquium:  Dr. Allison Ebert\, Medical College of Wisconsin
DESCRIPTION:Abstract:  My lab uses induced pluripotent stem cells (iPSCs) to model neurodevelopment and neurodegenerative diseases. We have two main branches of the lab. The first is to understand how viral infection alters neuron and astrocyte differentiation and function. The second is to identify the mechanisms underlying neuron malfunction and loss in a variety of neurodegenerative diseases\, including spinal muscular atrophy (SMA) and amyotrophic lateral sclerosis. This presentation will specifically focus on SMA\, which is a leading genetic cause of infant mortality and is characterized by loss of motor neurons in the spinal cord\, skeletal muscle atrophy\, and death. Although motor neuron loss is essential for the development of SMA\, growing evidence suggests that astrocytes are a key component of SMA pathogenesis. We have found that SMA astrocytes exhibit significant morphological and functional abnormalities that occur prior to overt motor neuron loss. We have further shown that astrocytes contribute to the SMA phenotype and do not support motor neuron development and survival\, but the underlying mechanisms are still unclear. I will discuss our new data identifying neuroinflammatory mediators and altered synaptic associated processes that could contribute to motor neuron loss.
URL:https://uwm.edu/biology/event/biological-sciences-colloquium-dr-allison-ebert-medical-college-of-wisconsin/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
X-TRIBE-STATUS:
GEO:43.0757204;-87.8840564
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=Lapham Hall N101 3209 N Maryland Ave Milwaukee WI 53211 United States;X-APPLE-RADIUS=500;X-TITLE=3209 N Maryland Ave:geo:-87.8840564,43.0757204
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20240223T160000
DTEND;TZID=America/Chicago:20240223T170000
DTSTAMP:20260516T085506
CREATED:20240220T171135Z
LAST-MODIFIED:20240220T171135Z
UID:10001339-1708704000-1708707600@uwm.edu
SUMMARY:Biological Sciences Colloquium: Dr. Manish Tiwari\, UW Madison
DESCRIPTION:Dr. Manish Tiwari\, Department of Bacteriology\, University of Wisconsin-Madison\, USA E-mail: mtiwari5@wisc.edu\, will present a talk about his work on “Tracking the Ancestry of Nod Factors: Exploring the Realms Beyond Alpha- and Beta-Rhizobia” \nThe Abstract is as follows: \nNod factors produced by rhizobia were identified as lipo-chitooligosaccharides (LCOs) more than 30 years ago. These LCOs are required for intracellular infection and nodule organogenesis in most rhizobia-legume associations. The nature of substitutions on the LCO backbone is a significant determinant of host specificity in this symbiosis. About ten years ago\, LCOs were also identified as produced by arbuscular mycorrhizal fungi. LCOs across rhizobia and fungi partly explain why several plant genes are required for LCO signal transduction and are involved in the common symbiotic pathway in legumes\, affecting both root nodulation and mycorrhizal associations. \nMore recently\, we demonstrated that LCOs are produced not only by arbuscular mycorrhizal fungi but by many fungi across the fungal kingdom (zygomycetes\, ascomycetes\, and basidiomycetes). These fungi exhibit various lifestyles as symbionts\, pathogens\, and saprotrophs; most are not associated with plants. We also demonstrated that many fungi respond to these LCOs in various dose-dependent ways\, suggesting that LCOs could be fungal quorum-sensing-like molecules. \nThe presence of genes potentially allowing the production of LCOs has been reported in Frankia Cluster II bacteria. We identified such genes and demonstrated LCO production in several Gram-positive bacteria\, such as Streptomyces bottropensis and Shimazuella kribbensis\, that do not fix nitrogen or seem to associate with plants. We will present our current model for the origin and role of LCO production in fungi and bacteria.
URL:https://uwm.edu/biology/event/biological-sciences-colloquium-dr-manish-tiwari-uw-madison/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
X-TRIBE-STATUS:
GEO:43.0757204;-87.8840564
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=Lapham Hall N101 3209 N Maryland Ave Milwaukee WI 53211 United States;X-APPLE-RADIUS=500;X-TITLE=3209 N Maryland Ave:geo:-87.8840564,43.0757204
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20240301T160000
DTEND;TZID=America/Chicago:20240301T170000
DTSTAMP:20260516T085506
CREATED:20240227T210756Z
LAST-MODIFIED:20240227T210756Z
UID:10001340-1709308800-1709312400@uwm.edu
SUMMARY:Biological Sciences Colloquium:  Dr. Chris Marshall\, Marquette University
DESCRIPTION:“Adaptations In Biofilms: From Clinics to Climate Change” \nThe Abstract is as follows: \nMy research program addresses two grand challenges in science: antimicrobial resistance and quantifying global biogeochemical cycling. In the first\, I am interested in how diversity and metabolic changes in biofilms contribute to the alarming and expanding problem of antibiotic resistance. In the second\, I study anaerobic metabolisms associated with biogeochemical cycles as a biotechnological and ecological source of innovation. Traditionally these disciplines don’t intersect. I would argue\, however\, that microbial ecology and evolution mediated by metabolic feedback lie at the core of each. Metabolic byproducts can open up new niches that influence eco-evolutionary dynamics and vice versa. Insights into diversification\, resilience\, resource competition\, and cooperation in one system (environment) can inform another (host). Furthermore\, the practical component uniting my research program is the study of ecology and evolution in anaerobic biofilms\, particularly those that experience limiting resources (e.g. mucosal surfaces or natural environments). In addition\, I am keenly interested in developing novel engineered devices and bioinformatic tools to address key scientific questions.
URL:https://uwm.edu/biology/event/biological-sciences-colloquium-dr-chris-marshall-marquette-university/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
X-TRIBE-STATUS:
GEO:43.0757204;-87.8840564
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=Lapham Hall N101 3209 N Maryland Ave Milwaukee WI 53211 United States;X-APPLE-RADIUS=500;X-TITLE=3209 N Maryland Ave:geo:-87.8840564,43.0757204
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20240308T160000
DTEND;TZID=America/Chicago:20240308T170000
DTSTAMP:20260516T085506
CREATED:20240305T161031Z
LAST-MODIFIED:20240305T161031Z
UID:10001341-1709913600-1709917200@uwm.edu
SUMMARY:Biological Sciences Colloquium:  Dr.  Joseph Hoyt\, Virginia Tech
DESCRIPTION:Dr. Hoyt from Virginia Tech will present a talk about his work entitled\, “Sit-and-Wait Pathogens: Environmental Pathogen Reservoirs and Infectious Disease Dynamics.” \nThe Abstract is as Follows: \nEmerging infectious diseases are recognized as a serious threat to wildlife populations\, and pathogen transmission is a fundamental component of disease systems governing the rate and extent of host impacts. Examining data across broad spatial and temporal time scales can help elucidate processes that lead to increases in host infections and subsequent population declines. Combining twelve years of data on host infection\, environmental reservoir dynamics\, and population trends we elucidate the contribution of environmental transmission to infectious disease dynamics for the emerging wildlife disease of bats\, white-nose syndrome (WNS). We find that the environmental reservoir is a key factor influencing bat infection and impacts across local and global scales. In addition\, the experimental removal of the pathogen causing WNS from the environment reduced bat infection and mortality. Finally\, we examined contributions of pathogen virulence to landscape-level disease patterns using both empirical field sampling and experimental infections. We find both pathogen strain and host species were important factors that contributed to variation in prevalence of the pathogen that causes snake fungal disease. More broadly\, our results highlight that determining the diverse processes that underlie patterns of pathogen transmission can serve as points of leverage for managing wildlife disease. \n 
URL:https://uwm.edu/biology/event/biological-sciences-colloquium-dr-joseph-hoyt-virginia-tech/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
X-TRIBE-STATUS:
GEO:43.0757204;-87.8840564
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=Lapham Hall N101 3209 N Maryland Ave Milwaukee WI 53211 United States;X-APPLE-RADIUS=500;X-TITLE=3209 N Maryland Ave:geo:-87.8840564,43.0757204
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20240315T160000
DTEND;TZID=America/Chicago:20240315T170000
DTSTAMP:20260516T085506
CREATED:20240312T172919Z
LAST-MODIFIED:20240312T172919Z
UID:10001342-1710518400-1710522000@uwm.edu
SUMMARY:Biological Sciences Colloquium:  Dr. Claire Richardson
DESCRIPTION:Dr. Claire Richardson\, University of Wisconsin-Madison\, will present a talk about her work entitled\, “Sustaining the Brain: Insights into Neuronal Maintenance from Ageless Animals to Lysosomal Degradation” \nResearch Description:    \nAging is the principal risk factor for cognitive decline and neurodegenerative disease. From worms to humans\, neuronal aging is associated with decay in cellular function and increased risk for disease pathologies. The Richardson Lab aims to understand the fundamental cell biology underlying neuronal aging\, which will lead to strategies for intervention.
URL:https://uwm.edu/biology/event/biological-sciences-colloquium-dr-claire-richardson/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
X-TRIBE-STATUS:
GEO:43.0757204;-87.8840564
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=Lapham Hall N101 3209 N Maryland Ave Milwaukee WI 53211 United States;X-APPLE-RADIUS=500;X-TITLE=3209 N Maryland Ave:geo:-87.8840564,43.0757204
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20240329T160000
DTEND;TZID=America/Chicago:20240329T170000
DTSTAMP:20260516T085506
CREATED:20240321T165523Z
LAST-MODIFIED:20240321T165523Z
UID:10001343-1711728000-1711731600@uwm.edu
SUMMARY:Biological Sciences Colloquium:  Drs. W.G. Stooksbury and H.T. Millen
DESCRIPTION:Drs. W.G. Stooksbury and H.T. Millen will present a talk about their work entitled\, “Substance Use Disorders and Addiction:  Neurobiological Mechanisms and Treatment Implications” \nThe Abstract is as follows: \nAddiction and substance use disorders are chronic and relapsing conditions characterized by compulsions to seek a substance\, loss of impulse control to limit intake resulting in increasing use\, and negative affective states when access to the substance is unavailable. Substance use is a significant contributor to mortality and morbidity world-wide. Despite the initial report released by the Surgeon General in 1964 regarding smoking and tobacco use\, nicotine continues to be a significant public health risk. In this discussion\, we will cover the current theories regarding the neurobiological mechanisms behind addiction with a focus on tobacco use disorder.  We will explore current FDA approved pharmacotherapies\, repetitive transcranial magnetic stimulation\, and emerging treatment options\, examining how their mechanisms of action modulate addiction pathways.
URL:https://uwm.edu/biology/event/biological-sciences-colloquium-drs-w-g-stooksbury-and-h-t-millen/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
X-TRIBE-STATUS:
GEO:43.0757204;-87.8840564
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=Lapham Hall N101 3209 N Maryland Ave Milwaukee WI 53211 United States;X-APPLE-RADIUS=500;X-TITLE=3209 N Maryland Ave:geo:-87.8840564,43.0757204
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20240405T160000
DTEND;TZID=America/Chicago:20240405T170000
DTSTAMP:20260516T085506
CREATED:20240403T193031Z
LAST-MODIFIED:20240403T193031Z
UID:10001344-1712332800-1712336400@uwm.edu
SUMMARY:Biological Sciences Colloquium:  Dr. Jean-Pierre Saint-Jeannet
DESCRIPTION:Dr. Jean-Pierre Saint-Jeannet\, New York University\, will present a talk about his work entitled\, “Understanding the Role of The Spliceosome in Craniofacial Syndromes: A Tale of Frogs and Embryonic Stem Cells.” \nThe Abstract is as Follows: \nSynopsis: Nager syndrome is a rare craniofacial and limb disorder characterized by midface retrusion\, micrognathia\, absent thumbs\, and radial hypoplasia. This disorder results from mutations in SF3B4 gene\, which encodes a core component of the spliceosome. While the spliceosome is present and functions in all cells of the body to remove introns and join exons from transcribed pre-mRNA\, many spliceosomopathies – including Nager syndrome – are often cell/tissue-specific in their pathology. In Nager syndrome patients it is the neural crest-derived craniofacial skeletal structures that are primarily affected. To understand the pathomechanism underlying this condition\, we have developed two models of Nager syndrome by knocking down SF3B4 in Xenopus tropicalis and in human embryonic stem cells. We will present and discuss some of our findings. \n 
URL:https://uwm.edu/biology/event/biological-sciences-colloquium-dr-jean-pierre-saint-jeannet/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
X-TRIBE-STATUS:
GEO:43.0757204;-87.8840564
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=Lapham Hall N101 3209 N Maryland Ave Milwaukee WI 53211 United States;X-APPLE-RADIUS=500;X-TITLE=3209 N Maryland Ave:geo:-87.8840564,43.0757204
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20240412T093000
DTEND;TZID=America/Chicago:20240412T150000
DTSTAMP:20260516T085506
CREATED:20240410T185042Z
LAST-MODIFIED:20240410T185446Z
UID:10001346-1712914200-1712934000@uwm.edu
SUMMARY:Spring 2024 Biological Sciences Research Symposium
DESCRIPTION:The Graduate Organization of Biological Sciences (GOBS)\, in conjunction with the Department of Biological Sciences\, presents the 2024 Biological Sciences Research Symposium. The symposium is designed to showcase our outstanding undergraduate and graduate students and their research in the department. Advance registration required. \nView this year’s program by clicking here!
URL:https://uwm.edu/biology/event/spring-2024-biological-sciences-research-symposium/
LOCATION:UWM Student Union Ballroom\, 2200 E. Kenwood Blvd\, Milwaukee\, WI\, 53201
CATEGORIES:Department
ATTACH;FMTTYPE=image/png:https://uwm.edu/biology/wp-content/uploads/sites/21/2023/09/download-2.png
X-TRIBE-STATUS:
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20240412T160000
DTEND;TZID=America/Chicago:20240412T170000
DTSTAMP:20260516T085506
CREATED:20240409T190253Z
LAST-MODIFIED:20240409T190253Z
UID:10001345-1712937600-1712941200@uwm.edu
SUMMARY:Biological Sciences Colloquium: Laura Rolfs
DESCRIPTION:Laura Rolfs will present a talk about his/her/their work entitled\, “The role of non-muscle myosins in zebrafish development and MYH9-related disease” \nThe Abstract is as Follows: \nMYH genes encode highly conserved actin-based motor proteins\, non-muscle myosins (NMIIs)\, which have essential roles in cell division\, cell migration\, and cell shape changes. Zebrafish have two myh9 genes (myh9a and myh9b) which encode for the NMIIA protein\, along with myh10 and myh14\, which encode for NMIIB and NMIIC\, respectively. To understand the role of myh genes in development\, we obtained a null mutant for the myh9a gene and generated null mutants for the myh9b and myh10 genes using CRISPR/Cas genome editing. myh14 was not examined due to the low sequence homology. Through our studies we identified myh9b\, not myh9a or myh10\, as the critical myh gene required for normal zebrafish development and morphogenesis. Consistent with this finding\, myh9a and myh10 homozygous mutants are viable through adulthood with no visible phenotypes. However\, myh9b homozygous mutants are semi-lethal and develop pericardial edema between 48 and 96 hours post fertilization\, a phenotype consistent with kidney dysfunction. This phenotype reverses shortly after onset\, leading us to hypothesize that there is redundancy or compensation by other myh genes and proteins in these mutants. This is supported by the finding that double mutants display more severe phenotypes earlier in development than single mutants. In the human population there are five clinical disorders resulting from mutations in the MYH9 gene that are classified as MYH9-related disease (MYH9-RD)\, with many patients developing kidney dysfunction. Examination of larval myh9b homozygous mutant kidney structure revealed severe defects including podocyte foot process effacement\, increased slit diaphragm size\, and protein precipitate in Bowman’s space. These results suggest that myh9b mutants can be used as a model to study the development and progression of MYH9-RD. Current experiments are further investigating glomerular function and the cell type specific role for myh9b in development.
URL:https://uwm.edu/biology/event/biological-sciences-colloquium-laura-rolfs/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
X-TRIBE-STATUS:
GEO:43.0757204;-87.8840564
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=Lapham Hall N101 3209 N Maryland Ave Milwaukee WI 53211 United States;X-APPLE-RADIUS=500;X-TITLE=3209 N Maryland Ave:geo:-87.8840564,43.0757204
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20240419T160000
DTEND;TZID=America/Chicago:20240419T170000
DTSTAMP:20260516T085506
CREATED:20240416T135054Z
LAST-MODIFIED:20240416T135054Z
UID:10001347-1713542400-1713546000@uwm.edu
SUMMARY:Biological Sciences Colloquium: Shanice Piango
DESCRIPTION:Shanice Piango\, UWM graduate student\, will present a talk about her work entitled\, “Germplasm Conservation Strategies for Understanding Fertility in Giant Kelp (Macrocystis Pyrifera)” \nThe Abstract is as Follows: \nMy research explores the application of germplasm conservation strategies in seaweed\, focusing on the fertility of stored gametophytes\, microbiome interactions with antibiotic treatment\, and germplasm longevity. As seaweed ecosystems face threats from climate change along with the rapidly growing seaweed aquaculture industry\, germplasm conservation emerges as a key strategy for preserving biodiversity and supporting aquaculture. Germplasm conservation is instrumental in sustaining biodiversity and ecosystem services\, particularly for improving the aquaculture of Macrocystis pyrifera. Our investigation delves into the challenges of declining gametophyte fertility over time\, investigating gene expression differences between sexes and what genes play major roles in successful reproduction\, examining the role of microbiome interactions and antibiotics in germplasm health\, and assesses strategies to enhance the longevity and viability of stored seaweed germplasm. \nThe presentation will begin at 4:00PM in Lapham Hall N101\, preceded by an informal reception from 3:45-4:00PM.
URL:https://uwm.edu/biology/event/biological-sciences-colloquium-shanice-piango/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
X-TRIBE-STATUS:
GEO:43.0757204;-87.8840564
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=Lapham Hall N101 3209 N Maryland Ave Milwaukee WI 53211 United States;X-APPLE-RADIUS=500;X-TITLE=3209 N Maryland Ave:geo:-87.8840564,43.0757204
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20240426T160000
DTEND;TZID=America/Chicago:20240426T170000
DTSTAMP:20260516T085506
CREATED:20240423T132525Z
LAST-MODIFIED:20240423T132525Z
UID:10001348-1714147200-1714150800@uwm.edu
SUMMARY:Biological Sciences Colloquium: Dr. Devanshi Khokhani
DESCRIPTION:Dr. Devanshi Khokhani will present a talk about her work entitled\, “Harnessing Rhizosphere Microbes to Foster Plant Health.” \nThe abstract is as follows: \nRhizosphere\, a narrow zone at the soil-root interface\, is an untapped resource for discovering beneficial microbes that can fight plant pathogens and increase crop yields in a sustainable way. Uncontrolled use of conventional agrochemicals such as pesticides and fertilizers used to manage crop yields affects soil health and eventually plant health. We study rhizosphere microbes of corn to develop robust biological control agents and biofertilizers. Through in vitro and growth chamber assays\, we tested the antagonistic activity of a bacterial synthetic community (SynComs)\, against some of the prominent corn root rot pathogens. We found that the SynCom significantly inhibited the growth of an oomycete and some fungal pathogens and now we are in the process of identifying inhibitory microbial products secreted by the community. Next\, to reduce our dependence on synthetic nitrogen fertilizers\, we sought to study cross-kingdom interactions of a fungal root endosymbiont\, called mycorrhizal fungi\, and nitrogen-fixing bacteria. Co-inoculation of the fungus with a robust nitrogen fixer increased the colonization of corn roots and improved the transfer of fixed N to corn\, with 16 to 25 % of nitrogen-derived from the atmosphere. These findings suggest that mycorrhizal fungi mediate the transfer of fixed nitrogen to plants and that the nitrogen-fixer also acts as a helper bacterium by enhancing the colonization of corn roots. Overall\, our results highlight the importance and potential of rhizosphere microbes towards sustainable management of plant health. \nThe presentation will begin at 4:00 PM in Lapham Hall N101\, preceded by an informal reception from 3:45 – 4:00 PM.
URL:https://uwm.edu/biology/event/biological-sciences-colloquium-dr-devanshi-khokhani/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
X-TRIBE-STATUS:
GEO:43.0757204;-87.8840564
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=Lapham Hall N101 3209 N Maryland Ave Milwaukee WI 53211 United States;X-APPLE-RADIUS=500;X-TITLE=3209 N Maryland Ave:geo:-87.8840564,43.0757204
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20240503T160000
DTEND;TZID=America/Chicago:20240503T170000
DTSTAMP:20260516T085506
CREATED:20240430T133814Z
LAST-MODIFIED:20240430T133814Z
UID:10001349-1714752000-1714755600@uwm.edu
SUMMARY:Biological Sciences Colloquium: Vidhya Basak
DESCRIPTION:Vidhya Basak\, UWM graduate student\, will present a talk about her work entitled\, “A New Level of Eukaryotic AMPK Regulation: Lessons From Yeast.” \nThe abstract is as follows: \nIn the Kuchin lab\, we focus on understanding the mechanisms by which eukaryotes respond to energy stress. Being able to respond to energy stress is quintessential for maintaining energy homeostasis. The AMP-activated protein kinase (AMPK) is the master regulator of energy homeostasis in eukaryotes from yeast to humans. Mammalian AMPK has been implicated in diseases from diabetes to cancer. AMPK of baker’s yeast (Saccharomyces cerevisiae) serves as an important model to understand eukaryotic AMPK signaling. Yeast AMPK responds to stresses caused by glucose/energy limitation and promotes utilization of alternative carbon sources. Like mammalian AMPK\, yeast AMPK is a heterotrimeric complex. It is composed of the catalytic α subunit (Snf1)\, one of three alternative targeting/scaffolding β subunits (Sip1\, Sip2\, or Gal83)\, and a regulatory γ subunit (Snf4). When energy levels drop\, yeast AMPK is known to be upregulated by two main mechanisms: 1) catalytic activation by phosphorylation of Thr210 of Snf1; 2) Gal83-dependent nuclear enrichment of the activated yeast AMPK complex. Here\, we present evidence for a new level of AMPK regulation. Thus far\, the AMPK complex has been assumed to assemble “by itself”. Our results suggest that yeast AMPK undergoes facilitated assembly aided by two paralogous WD40 repeat proteins. Our findings may have implications for AMPK regulation in other eukaryotes and inform research in human metabolic disease\, fungal pathogenesis\, and yeast biotechnology. \nThe presentation will begin at 4:00 PM in Lapham Hall N101\, preceded by an informal reception from 3:45 – 4:00PM.
URL:https://uwm.edu/biology/event/biological-sciences-colloquium-vidhya-basak/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
X-TRIBE-STATUS:
GEO:43.0757204;-87.8840564
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=Lapham Hall N101 3209 N Maryland Ave Milwaukee WI 53211 United States;X-APPLE-RADIUS=500;X-TITLE=3209 N Maryland Ave:geo:-87.8840564,43.0757204
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20240913T160000
DTEND;TZID=America/Chicago:20240913T170000
DTSTAMP:20260516T085506
CREATED:20240910T194911Z
LAST-MODIFIED:20240910T194911Z
UID:10001350-1726243200-1726246800@uwm.edu
SUMMARY:Biological Sciences Colloquium: Dr. Claire de la Cova
DESCRIPTION:Dr. Claire de la Cova\, assistant professor of biological sciences at UWM\, will present a talk about her work entitled\, “The very elegant patient: How the worm C. elegans provides insights into Raf signaling in disease.” \nThe summary is as follows: \n“Raf protein kinases act as Ras-GTP sensing components of the ERK signal transduction pathway in animal cells\, influencing cell proliferation\, differentiation\, and survival. In humans\, somatic and germline mutations in the genes BRAF and RAF1 are associated with cancers and developmental disorders. Our approach to investigate Raf signaling uses the roundworm Caenorhabditis elegans\, which has a single Raf ortholog termed LIN-45. I will share our insights into how Raf kinase activity\, protein localization\, and degradation are controlled in animals\, and how these mechanisms may impact human diseases.” \nThe presentation will begin at 4:00 PM in Lapham Hall N101\, preceded by an informal reception from 3:45 – 4:00 PM.
URL:https://uwm.edu/biology/event/biological-sciences-colloquium-dr-claire-de-la-cova/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
ATTACH;FMTTYPE=image/jpeg:https://uwm.edu/biology/wp-content/uploads/sites/21/2024/09/2024_September_13_delaCova.jpg
X-TRIBE-STATUS:
GEO:43.0757204;-87.8840564
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=Lapham Hall N101 3209 N Maryland Ave Milwaukee WI 53211 United States;X-APPLE-RADIUS=500;X-TITLE=3209 N Maryland Ave:geo:-87.8840564,43.0757204
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20240920T160000
DTEND;TZID=America/Chicago:20240920T170000
DTSTAMP:20260516T085506
CREATED:20240917T191140Z
LAST-MODIFIED:20240917T191146Z
UID:10001351-1726848000-1726851600@uwm.edu
SUMMARY:Biological Sciences Colloquium: Wendy Shelton
DESCRIPTION:Wendy Shelton\, UW-Milwaukee graduate student\, will present a talk about her work entitled\, “Exploring the causes and consequences of variation in flowering patterns.” \nThe abstract is as follows: \n“Flowering patterns often vary widely\, both within and among populations. Among-individual variation in flowering can affect the number of prospective mates\, the risk of mating with lower quality individuals\, and the likelihood of self-pollination. In this colloquium\, I describe two studies that explore variation in flowering patterns in monkeyflower (Mimulus ringens)\, a hermaphroditic herb. In the first study\, I employed an experimental design that minimized environmental variation and allowed me to quantify substantial flowering pattern variation due primarily to genetic factors. In the second study\, I investigated the relationship between genetic diversity and variation in mating opportunity due to among-individual heterogeneity in flower production. My work enhances our understanding of the evolution of flower deployment strategies and associated mating patterns.” \nThe presentation will begin at 4:00 PM in Lapham Hall N101\, preceded by an informal reception from 3:45 – 4:00 PM.
URL:https://uwm.edu/biology/event/biological-sciences-colloquium-wendy-shelton/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
ATTACH;FMTTYPE=image/jpeg:https://uwm.edu/biology/wp-content/uploads/sites/21/2024/09/2024-Sep-20-Shelton.jpg
X-TRIBE-STATUS:
GEO:43.0757204;-87.8840564
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=Lapham Hall N101 3209 N Maryland Ave Milwaukee WI 53211 United States;X-APPLE-RADIUS=500;X-TITLE=3209 N Maryland Ave:geo:-87.8840564,43.0757204
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20240927T160000
DTEND;TZID=America/Chicago:20240927T170000
DTSTAMP:20260516T085506
CREATED:20240924T182351Z
LAST-MODIFIED:20240924T182419Z
UID:10001352-1727452800-1727456400@uwm.edu
SUMMARY:Biological Sciences Colloquium: Dr. Carole Labonne
DESCRIPTION:Dr. Carole Labonne of Northwestern University will present a talk about her work entitled\, “Control of Stem Cell Attributes in Early Vertebrate Development.” \nThe presentation will begin at 4:00 PM in Lapham Hall N101\, preceded by an informal reception from 3:45 – 4:00 PM.
URL:https://uwm.edu/biology/event/biological-sciences-colloquium-dr-carole-labonne/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
ATTACH;FMTTYPE=image/jpeg:https://uwm.edu/biology/wp-content/uploads/sites/21/2024/09/2024-Sep-27-Labonne.jpg
X-TRIBE-STATUS:
GEO:43.0757204;-87.8840564
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=Lapham Hall N101 3209 N Maryland Ave Milwaukee WI 53211 United States;X-APPLE-RADIUS=500;X-TITLE=3209 N Maryland Ave:geo:-87.8840564,43.0757204
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20240928T120000
DTEND;TZID=America/Chicago:20240928T170000
DTSTAMP:20260516T085506
CREATED:20240924T205921Z
LAST-MODIFIED:20240924T205921Z
UID:10001353-1727524800-1727542800@uwm.edu
SUMMARY:UWM Biological Sciences Greenhouse: Doors Open Milwaukee
DESCRIPTION:Join us this weekend\, September 28th and 29th\, from 12:00-5:00PM at the UWM Biological Sciences Greenhouse for Doors Open Milwaukee! The greenhouse is located at the NWQ-C building\, 1930 E Hartford Ave\, in room 4600.
URL:https://uwm.edu/biology/event/uwm-biological-sciences-greenhouse-doors-open-milwaukee/2024-09-28/
LOCATION:Northwest Quadrant C\, Room 4600\, 1930 E Hartford Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Department
ATTACH;FMTTYPE=image/jpeg:https://uwm.edu/biology/wp-content/uploads/sites/21/2024/09/Greenhouse_Doors-Open-Milwaukee-Slide.jpg
X-TRIBE-STATUS:
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20240929T120000
DTEND;TZID=America/Chicago:20240929T170000
DTSTAMP:20260516T085506
CREATED:20240924T205921Z
LAST-MODIFIED:20240924T205921Z
UID:10001354-1727611200-1727629200@uwm.edu
SUMMARY:UWM Biological Sciences Greenhouse: Doors Open Milwaukee
DESCRIPTION:Join us this weekend\, September 28th and 29th\, from 12:00-5:00PM at the UWM Biological Sciences Greenhouse for Doors Open Milwaukee! The greenhouse is located at the NWQ-C building\, 1930 E Hartford Ave\, in room 4600.
URL:https://uwm.edu/biology/event/uwm-biological-sciences-greenhouse-doors-open-milwaukee/2024-09-29/
LOCATION:Northwest Quadrant C\, Room 4600\, 1930 E Hartford Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Department
ATTACH;FMTTYPE=image/jpeg:https://uwm.edu/biology/wp-content/uploads/sites/21/2024/09/Greenhouse_Doors-Open-Milwaukee-Slide.jpg
X-TRIBE-STATUS:
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20241011T160000
DTEND;TZID=America/Chicago:20241011T170000
DTSTAMP:20260516T085506
CREATED:20241008T191305Z
LAST-MODIFIED:20241008T191305Z
UID:10001355-1728662400-1728666000@uwm.edu
SUMMARY:Biological Sciences Colloquium: Battle of the Organisms
DESCRIPTION:Please join us for this special colloquium event: Battle of the Organisms! Participating labs from Biological Sciences each chose a lab member to represent the organism they study. Presenters have 5-minutes to convince you that their organism is the greatest. You can expect unique\, organism-themed snacks\, persuasive presentations\, the occasional organism-to-organisms trash talk\, and a round of voting for best\, coolest\, and cutest organism. This is a great opportunity to learn about the diverse organisms we study in the Biological Sciences department. \nThe presentation will begin at 4:00 PM in Lapham Hall N101\, preceded by an informal reception from 3:45 – 4:00 PM.
URL:https://uwm.edu/biology/event/biological-sciences-colloquium-battle-of-the-organisms/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
ATTACH;FMTTYPE=image/jpeg:https://uwm.edu/biology/wp-content/uploads/sites/21/2024/10/2024-Oct-11-Battle-of-the-Organisms.jpg
X-TRIBE-STATUS:
GEO:43.0757204;-87.8840564
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=Lapham Hall N101 3209 N Maryland Ave Milwaukee WI 53211 United States;X-APPLE-RADIUS=500;X-TITLE=3209 N Maryland Ave:geo:-87.8840564,43.0757204
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20241018T160000
DTEND;TZID=America/Chicago:20241018T170000
DTSTAMP:20260516T085506
CREATED:20241015T183227Z
LAST-MODIFIED:20241015T183913Z
UID:10001356-1729267200-1729270800@uwm.edu
SUMMARY:Biological Sciences Colloquium: Dr. Kyle Leistikow
DESCRIPTION:Dr. Kyle Leistikow\, research manager at Microbial Discovery Group (MDG)\, will present a talk about his work entitled\, “From Soil to Solution: Discovering Bacillus subtilis Peptides That Battle Biofilm-Forming Superbugs.” \nThe abstract is as follows: \n“Multidrug-resistant Staphylococcus auerus poses a critical challenge to both human and animal health\, largely due to its ability to form biofilms that protect it from antibiotics and promote resistance. To help combat this issue\, Bacillus subtilis\, a probiotic bacterium\, has emerged as a natural source of biofilm-disrupting compounds. After screening over 1\,000 Bacilius isolates\, we identified a unique strain\, B. subtilis 6D1\, that produces peptides capable of disassembling mature S. aureus biofilms and enhancing antibiotic sensitivity. This talk will explore the journey from soil to solution\, unearthing the powerful antibiofilm properties of Bacillus peptides and their potential to combat superbug infections.” \nThe presentation will begin at 4:00 PM in Lapham Hall N101\, preceded by an informal reception from 3:45 – 4:00 PM.
URL:https://uwm.edu/biology/event/biological-sciences-colloquium-dr-kyle-leistikow/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
ATTACH;FMTTYPE=image/jpeg:https://uwm.edu/biology/wp-content/uploads/sites/21/2024/10/2024-Oct-18-Leistikow.jpg
X-TRIBE-STATUS:
GEO:43.0757204;-87.8840564
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=Lapham Hall N101 3209 N Maryland Ave Milwaukee WI 53211 United States;X-APPLE-RADIUS=500;X-TITLE=3209 N Maryland Ave:geo:-87.8840564,43.0757204
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20241025T160000
DTEND;TZID=America/Chicago:20241025T170000
DTSTAMP:20260516T085506
CREATED:20241022T183806Z
LAST-MODIFIED:20241022T183806Z
UID:10001357-1729872000-1729875600@uwm.edu
SUMMARY:Biological Sciences Colloquium: Dr. Mingzi Xu
DESCRIPTION:Dr. Mingzi Xu from the University of Minnesota will present a talk about her work entitled\, “The evolution and genomics of sexual signals and mating preferences.” \nThe abstract is as follows: \n“Sexual signals and mating preferences are key to sexual selection and speciation. The evolution of sexual signals and preferences involves trait divergence within each sex and coevolution between males and females. In addition\, signals and preferences are susceptible to environmental perturbations\, presenting a challenge to the stability of signaling systems. What genetic and genomic mechanisms govern the evolution of sexual signaling systems and maintain their stability against environmental perturbation is a crucial outstanding question in evolutionary biology. \nIn this talk\, I will present a study on the genetic basis of signal-preference coevolution in Laupala crickets\, where male song pulse rate and female preference for pulse rate have coevolved repeatedly. Using QTL fine mapping\, I have identified 3 pairs of co-localizing song and preference loci in the Laupala genome\, providing strong evidence for genetic coupling\, a long-dismissed hypothesis. I have also identified promising candidate genes that may pleiotrophically regulate male singing and female preference. I will then present new research in my lab on how environmental perturbations such as chemical pollutants and temperature fluctuations affect coordination between signals and preferences\, as well as neurogenomic mechanisms maintaining the stability of the communication system.” \nThe presentation will begin at 4:00 PM in Lapham Hall N101\, preceded by an informal reception from 3:45 – 4:00 PM.
URL:https://uwm.edu/biology/event/biological-sciences-colloquium-dr-mingzi-xu/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
X-TRIBE-STATUS:
GEO:43.0757204;-87.8840564
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=Lapham Hall N101 3209 N Maryland Ave Milwaukee WI 53211 United States;X-APPLE-RADIUS=500;X-TITLE=3209 N Maryland Ave:geo:-87.8840564,43.0757204
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20241101T160000
DTEND;TZID=America/Chicago:20241101T170000
DTSTAMP:20260516T085506
CREATED:20241029T190037Z
LAST-MODIFIED:20241029T190037Z
UID:10001358-1730476800-1730480400@uwm.edu
SUMMARY:Biological Sciences Colloquium: Dr. Ethan Degner
DESCRIPTION:Dr. Ethan Degner of Wisconsin Lutheran College will present a talk about his work entitled\, “Chronicling a mosquito’s sex life from intromission to oviposition.” \nThe abstract is as follows: \n“Each year\, mosquito-borne infections kill hundreds of thousands and sicken hundreds of millions more. Controlling populations of mosquitoes is a public health imperative\, but despite decades of effort and technological advances\, mosquitoes remain humanity’s number one killer.  \nManipulating mosquito reproduction offers a promising avenue by which mosquito populations may be controlled\, but doing so requires an intimate understanding of mosquito reproduction\, from mating to egg-laying and a host of events in between. In this seminar\, I use the yellow fever mosquito Aedes aegypti to chronicle a mosquito’s reproductive life\, highlighting the modifications that a mosquito’s sperm undergo prior to fertilization. I also present efforts to catalog the proteins and transcripts involved in these events. Proper sperm function within a female is a requirement for producing the next generation of pathogen-transmitting mosquitoes\, and therefore understanding the molecular and cellular underpinnings that govern mosquito reproduction may allow new methods for mosquito control.” \nThe presentation will begin at 4:00 PM in Lapham Hall N101\, preceded by an informal reception from 3:45 – 4:00 PM.
URL:https://uwm.edu/biology/event/biological-sciences-colloquium-dr-ethan-degner/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
ATTACH;FMTTYPE=image/jpeg:https://uwm.edu/biology/wp-content/uploads/sites/21/2024/10/2024-Nov-01-Degner.jpg
X-TRIBE-STATUS:
GEO:43.0757204;-87.8840564
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=Lapham Hall N101 3209 N Maryland Ave Milwaukee WI 53211 United States;X-APPLE-RADIUS=500;X-TITLE=3209 N Maryland Ave:geo:-87.8840564,43.0757204
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20241107T170000
DTEND;TZID=America/Chicago:20241107T190000
DTSTAMP:20260516T085506
CREATED:20241104T200827Z
LAST-MODIFIED:20241104T201447Z
UID:10001359-1730998800-1731006000@uwm.edu
SUMMARY:Graduate School Open House
DESCRIPTION:Join us at the Graduate School’s In-Person Open House event to learn more about Biological Sciences! The Graduate School will also pay the application fee for all applicants who attend the Open House (fee waiver eligibility requirements outlined here). \nClick here for more details and to register. 
URL:https://uwm.edu/biology/event/graduate-school-open-house-4/
LOCATION:Union Wisconsin Room East\, 2200 East Kenwood Blvd\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Department
X-TRIBE-STATUS:
GEO:43.0752308;-87.881425
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=Union Wisconsin Room East 2200 East Kenwood Blvd Milwaukee WI 53211 United States;X-APPLE-RADIUS=500;X-TITLE=2200 East Kenwood Blvd:geo:-87.881425,43.0752308
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20241108T160000
DTEND;TZID=America/Chicago:20241108T170000
DTSTAMP:20260516T085506
CREATED:20241105T194601Z
LAST-MODIFIED:20241105T194735Z
UID:10001360-1731081600-1731085200@uwm.edu
SUMMARY:Biological Sciences Colloquium: Dr. Eillen Tecle
DESCRIPTION:Dr. Eillen Tecle\, Assistant Professor in the Department of Microbiology and Immunology at the Medical College of Wisconsin\, will present a talk about her work entitled\, “Purine nucleotide salvage enzymes regulate epithelial cell resistance to infection in C. elegans.”\n\n\nThe abstract is as follows:\n\n\n“The Intracellular Pathogen Response (IPR) was identified as a common host transcriptional response to diverse natural intracellular pathogens in C. elegans\, including the Orsay virus\, as well as Microsporidia\, which cause the most observed infection in wild-caught C. elegans. IPR genes in C. elegans are distinct from those induced by heat shock and other stressors. Constitutive IPR activation protects C. elegans from intracellular pathogen infection while compromising development and lifespan. Despite its dramatic effects on host physiology\, we know little about how the IPR is activated\, regulated\, and promotes defense. However\, we have identified a novel role for the C. elegans orthologs of human purine metabolism genes as negative regulators of the IPR. We are currently working to understand the mechanism by which these enzymes and\, more broadly\, purine metabolism regulate immunity.”\n\n\nThe presentation will begin at 4:00 PM in Lapham Hall N101\, preceded by an informal reception from 3:45 – 4:00 PM.
URL:https://uwm.edu/biology/event/biological-sciences-colloquium-dr-eillen-tecle/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
ATTACH;FMTTYPE=image/jpeg:https://uwm.edu/biology/wp-content/uploads/sites/21/2024/11/2024-Nov-08-Tecle.jpg
X-TRIBE-STATUS:
GEO:43.0757204;-87.8840564
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=Lapham Hall N101 3209 N Maryland Ave Milwaukee WI 53211 United States;X-APPLE-RADIUS=500;X-TITLE=3209 N Maryland Ave:geo:-87.8840564,43.0757204
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20241115T160000
DTEND;TZID=America/Chicago:20241115T170000
DTSTAMP:20260516T085506
CREATED:20241112T210203Z
LAST-MODIFIED:20241112T210203Z
UID:10001361-1731686400-1731690000@uwm.edu
SUMMARY:Biological Sciences Colloquium: Dr. Chris Quinn
DESCRIPTION:Dr. Chris Quinn of UW-Milwaukee will present a talk about his work entitled\, “Harnessing human genetics to investigate the development and degeneration of axons in C. elegans.” \nThe abstract is as follows: \n“Genome sequencing studies have generated a list of de novo variants that are associated with neurodevelopmental disorders such as autism and intellectual disability. However\, little is known about how variants in these genes can disrupt neuronal cell biology to cause defects in neurodevelopment. Our laboratory is using these variants to uncover novel mechanisms that regulate neuronal development in C. elegans. In the first part of this talk\, I will focus on our work with the RBM-26(RBM26/27) RNA binding protein. We found that mutations in rbm-26 cause mitochondrial dysfunction\, axon degeneration and axon targeting defects. Mechanistically\, we discovered that RBM-26 negatively regulates the MALS-1 mitoribosomal assembly factor and that this interaction is required to protect against axon degeneration and axon targeting defects. In the second part\, I will talk about the anc-1 ortholog of SYNE1\, which has been associated with autism and bipolar disorder. We have found that mutations in anc-1 disrupt the polarization of axon growth by disrupting the localization of mitochondria within the neuron. These studies highlight the roles that autism-associated genes can play in promoting mitochondrial function and how disruptions in these processes can lead to the defects in neurodevelopment that underlie autism.” \nThe presentation will begin at 4:00 PM in Lapham Hall N101\, preceded by an informal reception from 3:45 – 4:00 PM.
URL:https://uwm.edu/biology/event/biological-sciences-colloquium-dr-chris-quinn/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
ATTACH;FMTTYPE=image/jpeg:https://uwm.edu/biology/wp-content/uploads/sites/21/2024/11/2024-Nov-15-Quinn.jpg
X-TRIBE-STATUS:
GEO:43.0757204;-87.8840564
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=Lapham Hall N101 3209 N Maryland Ave Milwaukee WI 53211 United States;X-APPLE-RADIUS=500;X-TITLE=3209 N Maryland Ave:geo:-87.8840564,43.0757204
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20241122T160000
DTEND;TZID=America/Chicago:20241122T170000
DTSTAMP:20260516T085506
CREATED:20241119T195109Z
LAST-MODIFIED:20241119T195109Z
UID:10001362-1732291200-1732294800@uwm.edu
SUMMARY:Biological Sciences Colloquium: Claudia Rodriguez
DESCRIPTION:Claudia Rodriguez\, graduate student of Biological Sciences at UW-Milwaukee\, will present a talk about her work entitled\, “An alternative mode of signal transduction by the EGL-15 FGF receptor in Caenorhabditis elegans.” \nThe abstract is as follows: \n“How is an animal body built and maintained? The answers lie in animal development\, which is regulated by cell signaling modules present in every animal\, from worms to mammals. One of these modules involves Fibroblast Growth Factors (FGFs) and their receptors (FGFRs)\, which stimulate Ras and the downstream kinases Raf\, MEK\, and ERK.  The Caenorhabditis elegans FGFR\, termed EGL-15\, is required in the sex myoblasts (SMs) for their cell migration during post-embryonic development\, and in the hypodermis (Hyp7) for homeostatic fluid balance throughout life. To investigate cell-specific differences between the SMs and Hyp7\, we used the kinase reporter ERK-KTR to assess activation of ERK. We found that EGL-15 utilized different signaling mechanisms in the SMs and Hyp7 and identified the IRS/DOK-like protein SOC-3 as required for EGL-15 signaling in Hyp7. This work highlights how one receptor can use cell-specific signaling mechanisms to achieve diverse developmental outcomes.” \nThe presentation will begin at 4:00 PM in Lapham Hall N101\, preceded by an informal reception from 3:45 – 4:00 PM.
URL:https://uwm.edu/biology/event/biological-sciences-colloquium-claudia-rodriguez/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
ATTACH;FMTTYPE=image/jpeg:https://uwm.edu/biology/wp-content/uploads/sites/21/2024/11/2024-Nov-22-Rodriguez.jpg
X-TRIBE-STATUS:
GEO:43.0757204;-87.8840564
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=Lapham Hall N101 3209 N Maryland Ave Milwaukee WI 53211 United States;X-APPLE-RADIUS=500;X-TITLE=3209 N Maryland Ave:geo:-87.8840564,43.0757204
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20250131T160000
DTEND;TZID=America/Chicago:20250131T170000
DTSTAMP:20260516T085506
CREATED:20250128T151507Z
LAST-MODIFIED:20250128T151507Z
UID:10001363-1738339200-1738342800@uwm.edu
SUMMARY:Biological Sciences Colloquium: Jill McClary-Gutierrez
DESCRIPTION:Jill McClary-Gutierrez\, Biological Safety Officer at UW-Milwaukee\, will present a talk about her work entitled\, “From LAIs to AI: History and current trends in biosafety & biosecurity.” \nThe abstract is as follows: \n“Even before the establishment of germ theory in the late 1800s\, humans have studied disease-causing organisms and\, in turn\, developed practices for working with those materials safely. However\, it wasn’t until the late 1900s that lab-associated infections (LAIs) were identified as a significant threat to the health of research and clinical scientists\, leading to the development of modern biosafety principles. Nowadays\, in the golden age of molecular biology\, new biological research tools are being developed at an incredible rate and can be implemented with ease for studies spanning a wide range of disciplines\, from physics to anthropology. In this talk\, I’ll discuss both the origins of biosafety for preventing LAIs\, as well as current trends in biosafety & biosecurity policy related to gene drives\, gain-of-function research\, and artificial intelligence. I’ll also provide a brief overview of UWM’s Biosafety Program and share what it’s like to work as a biosafety professional in a post-pandemic world.” \nThe presentation will begin at 4:00 PM in Lapham Hall N101\, preceded by an informal reception from 3:45 – 4:00 PM.
URL:https://uwm.edu/biology/event/biological-sciences-colloquium-jill-mcclary-gutierrez/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
ATTACH;FMTTYPE=image/jpeg:https://uwm.edu/biology/wp-content/uploads/sites/21/2025/01/2025-Jan-31-McClary-Gutierrez.jpg
X-TRIBE-STATUS:
GEO:43.0757204;-87.8840564
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=Lapham Hall N101 3209 N Maryland Ave Milwaukee WI 53211 United States;X-APPLE-RADIUS=500;X-TITLE=3209 N Maryland Ave:geo:-87.8840564,43.0757204
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20250214T160000
DTEND;TZID=America/Chicago:20250214T170000
DTSTAMP:20260516T085506
CREATED:20250211T153216Z
LAST-MODIFIED:20250211T153313Z
UID:10001364-1739548800-1739552400@uwm.edu
SUMMARY:Biological Sciences Colloquium: Drew Little
DESCRIPTION:Drew Little\, Ph.D. Candidate at UW-Milwaukee\, will present a talk entitled\, “Female interactions and their roles in mate choice.” \nThe abstract is as follows: \n“Currently\, many scientific studies in courtship emphasize the behavior and traits of males in determining mate choice. While incredibly successful\, this scope has led to misconceptions about the complexity of females when assessing potential mates. Using Enchenopa binotata as a model\, I will be challenging the misconceptions that (1) female interactions are simple; and (2)\, that female mate choice is only informed by the cues of courting males. To make my case I will be presenting evidence of the complex interactions of females during courtship\, that females interpret their social environment when assessing potential mates\, and that this interpretation can lead to maternal effects on offspring mate choice and courtship behaviors.” \nThe presentation will begin at 4:00 PM in Lapham Hall N101\, preceded by an informal reception from 3:45-4:00 PM.
URL:https://uwm.edu/biology/event/biological-sciences-colloquium-drew-little/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
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BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20250221T160000
DTEND;TZID=America/Chicago:20250221T170000
DTSTAMP:20260516T085506
CREATED:20250218T160213Z
LAST-MODIFIED:20250218T160213Z
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SUMMARY:Biological Sciences Colloquium: Dr. Matthew Shoulders
DESCRIPTION:Dr Matthew Shoulders of MIT will present a talk about his work entitled\, “Collagen Folding and Assembly in the Secretory Pathway.” \nThe abstract is as follows: \n“Collagen is the most abundant protein in humans and the molecular scaffold for animal life. Yet\, much remains to be elucidated regarding how cells successfully fold\, quality control\, and secrete this fundamental and uniquely complex component of the extracellular matrix. Progress towards defining how procollagen trimers are assembled with correct stoichiometries and composition will be discussed. Discoveries regarding key roles of sugar modifications in ensuring collagen proteostasis will also be presented. Connections to diseases of the extracellular matrix and potential therapeutic opportunities will be integrated throughout.” \nThe presentation will begin at 4:00 PM in Lapham Hall N101\, preceded by an informal reception from 3:45 – 4:00 PM.
URL:https://uwm.edu/biology/event/biological-sciences-colloquium-dr-matthew-shoulders/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
ATTACH;FMTTYPE=image/jpeg:https://uwm.edu/biology/wp-content/uploads/sites/21/2025/02/Feb-21-Shoulders.jpg
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BEGIN:VEVENT
DTSTART;TZID=America/Chicago:20250228T160000
DTEND;TZID=America/Chicago:20250228T170000
DTSTAMP:20260516T085506
CREATED:20250227T154219Z
LAST-MODIFIED:20250227T154219Z
UID:10001366-1740758400-1740762000@uwm.edu
SUMMARY:Biological Sciences Colloquium: Dr. Caroline Turner
DESCRIPTION:Dr. Caroline Turner of Loyola University will present a talk about her work entitled\, “Effects of resource limitation on the evolution of biofilm formation and antibiotic resistance.” \nThe Abstract is as follows: \n“Growth and reproduction of organisms is frequently limited by the availability of food resources\, often by the availability of one particular limiting element. Adaptation to this nutrient scarcity is a key way in which organisms can improve their evolutionary fitness in these environments. However\, we know little about how nutrient limitation alters the evolution of key microbial traits that impact humans\, such as growth of biofilms and resistance to antibiotics. I use experimental evolution\, evolving bacteria under controlled conditions in the laboratory\, to test how variation in resource availability affects the evolution of biofilm formation and of antibiotic resistance.” \nThe presentation will begin at 4:00 PM in Lapham Hall N101\, preceded by an informal reception from 3:45 – 4:00 PM.
URL:https://uwm.edu/biology/event/biological-sciences-colloquium-dr-caroline-turner/
LOCATION:Lapham Hall\, N101\, 3209 N Maryland Ave\, Milwaukee\, WI\, 53211\, United States
CATEGORIES:Colloquia
ATTACH;FMTTYPE=image/jpeg:https://uwm.edu/biology/wp-content/uploads/sites/21/2025/02/Feb-28-Turner.jpg
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END:VEVENT
END:VCALENDAR