Mahsa Ranji, Ph.D.

Ranji, Mahsa
, ranji@uwm.edu(414) 229-5889
Eng & Math Sciences 1195
Associate Professor
Electrical Engineering

Founder and Director of the Biophotonics Lab

Professor Ranji has openings for graduate students with strong background in Optics and are especially interested in hands-on experiments for biomedical applications. Please send your CV and a brief description of background and research interests by email.

Education:

  • Ph.D., Electrical Engineering, University of Pennsylvania, Philadelphia, Pennsylvania, 2007.
  • M.S., Electrical Engineering, Khaje Nasir Toosi University of Technology, Tehran, Iran, 2000.
  • B.S., Electrical Engineering, Sharif University of Technology, Tehran, Iran, 1998.

Research Focus:

  • Bio-photonics.
  • Bio-instrumentation.
  • Fluorescence imaging.
  • Noninvasive optical tissue diagnostics.
  • Optics and Electromagnetics.

Patent

  • J.H. Gorman, R.C. Gorman, M. Ranji, “In vivo Measurement of Mitochondrial Function,” US patent 8473036, June 2013.

Selected Publications

  • Z. Ghanian, S. Maleki, F. Assadi-Porter and M. Ranji,   " Optical imaging of mitochondrial redox state in rodent models with 3-iodothyronamine," Journal of Experimental Medicine and Biology, Vol. 239, pp. 151- 158, DOI 10.1002/jbio.201300033, Dec. 2013.
  • R. Sepehr, S. Audi, K. Staniszewski, E. R. Jacobs, and M. Ranji,   “Novel Flurometric Tool to Assess Mitochondrial Redox State of Isolated Perfused Rat Lungs after Exposure to Hyperoxia,” IEEE Journal of Translational Engineering in Health and Medicine, Vol. 1, No. 1, 1500210-1_1500210-10, Nov. 2013.
  • Z. Ghanian, S. Maleki, C.M. Sorenson, SunYoung Park, N. Sheibani and M. Ranji,   “Organ specific optical imaging of mitochondrial redox state in a rodent model of hereditary hemorrhagic telangiectasia-1,” Journal of Biophotonics, Vol. 6, No. 6, June 2013.
  • Z. Ghanian, M. MasoudiMotlagh, S. Maleki, Z. Bolandnazar, F. Assadi-Porter, M. Ranji,   " Optical Redox Imaging of Metabolic Dysfunction in Polycystic Ovary Syndrome," BMES Annual conference, Seattle, Sept. 2013.
  • R. Sepehr, S. Audi, S. Maleki, A.L. Eis, G.G. Konduri, M. Ranji,   “Optical Imaging of Lipopolysaccharide-induced Oxidative Stress in Acute Lung Injury from Hyperoxia and Sepsis,” Journal of Innovative Optical Health Sciences (JIOHS), Vol. 6, No.3 June 2013.
  • W. Linz, G. Michalak, M. MasoudiMotlagh, N. Seo, M. Ranji,  "Hand function assessment of stroke patients using non-invasive surface near-infrared spectroscopy,"   Great Lake Biomedical Conference, GE Healthcare, Milwaukee, April 2013 (awarded third place).
  • Z. Ghanian, S. Maleki, C.M. Sorenson, N. Sheibani, M. Ranji,  "Optical Imaging of Cellular Redox State Related to Retinopathy Dysfunction in Endoglin Heterozygous (Eng+/-) Mice,"   UWM CEAS Research Day, April 2013.
  • R. Sepehr, K. Staniszewski, E. R. Jacobs, S. Audi, and M. Ranji, "Fluorometry of ischemia reperfused rat lungs in vivo."   Proceeding of SPIE BIOS, San Francisco, Jan. 2013.
  • Z. Ghanian, S. Maleki, S. Gopalakrishnan, R. Sepehr, J. T. Eells and M. Ranji, "Optical imaging of oxidative stress in rodent model of retinitis pigmentosa."   Proceeding of SPIE BIOS, San Francisco, Jan. 2013.
  • Sepideh Maleki, Sandeep Gopalakrishnan, Reyhaneh Sepehr, Zahra Ghanian, Heather Schmitt, Janis Eells, Mahsa Ranji, "Optical imaging of tissue mitochondrial redox state in rodent model of retinitis pigmentosa."  Journal of Biomedical Optics, Vol. 18, No. 1, Jan 2013 (Selected as cover page).
  • Kevin Staniszewski, Said H. Audi, Reyhaneh Sepehr, Elizabeth R. Jacobs, and Mahsa Ranji, "Surface Fluorescence Studies of Tissue Mitochondrial Redox State in Isolated Perfused Rat Lungs."  Annals of Biomedical Engineering, Vol. 41, Jan. 2013.
  • Reyhaneh Sepehr, Kevin Staniszewski, Sepideh Maleki, Elizabeth R. Jacobs, Said Audi, Mahsa Ranji, "Optical imaging of tissue mitochondrial redox state in intact rat lungs in two models of pulmonary oxidative stress."  Journal of Biomedical Optics, Vol. 17, No. 4, April 2012.
  • Sepideh Maleki, Reyhaneh Sepehr, Kevin Staniszewski, Nader Sheibani, Christine M. Sorenson, and Mahsa Ranji, "Mitochondrial redox studies of oxidative stress in kidneys from diabetic mice."  Journal of Biomedical Optics Express, Biomedical Optics Express, Vol. 3, No. 2, pp. 273-281, Feb. 2012 (Selected as cover page).
  • Reyhaneh Sepehr, Sepideh Maleki, Kevin Staniszewski, Said Audi, Mahsa Ranji, "Optical Studies of Mitochondrial Redox State in Normoxic and Hyperoxic Rat Lung Tissue."   SPIE Photonics West proceeding, San Francisco 2012.
  • S Maleki, R. Sepehr, K. Staniszewski, N Sheibani, C.M. Sorenson, M. Ranji, "Optical Cryoimaging of Kidney Mitochondrial Redox State during Diabetes."   SPIE Photonics West proceeding, San Francisco 2012.
  • Kevin Staniszewski, Reyhaneh Sepehr, Christine M. Sorenson, Nader Sheibani, Mahsa Ranji, "Quantification and Classification of Retinopathic Injury Using Image Cytometry and Vasculature Feature Extraction."   SPIE Photonics West proceeding, San Francisco 2012.
  • Reyhaneh Sepehr, Kevin Staniszewski, Sepideh Maleki, Nader Sheibani, Christine Sorenson, Mahsa Ranji, "Optical Cryoimaging of Kidney Mitochnodrial Redox States and the Effect of BCL-2 Family Expression."   Proc. BMES, Hartford, 2011.
  • Muneaki Matsubara, Mahsa Ranji, Bradley G. Leshnower, Mio Noma, Sarah J Ratcliffe, and Britton Chance, Robert C. Gorman, Joseph H. Gorman III, "The Influence of Cyclosporine on Mitochondrial Function during Myocardial Ischemia and Reperfusion,"   Annals of Thoracic Surgery, vol. 89, pp. 1532-7, May 2010.
  • Mahsa Ranji, Shoko Nioka, Lin Z. Li, He N. Xu, Dwight L. Jaggard and Britton Chance, "Fluorescent Images of Mitochondrial Redox States of in Situ Mouse Hypoxic Ischemic Intestines,"   Journal of Innovative Optical Health Sciences (JIOHS), Vol. 2, No. 4, pp. 365–374, Dec. 2009.
  • Lin Z. Li, He N. Xu, Mahsa Ranji, Shoko Nioka, and Britton Chance, "Mitochondrial Redox Imaging for Cancer Diagnosis and Therapy,"   Journal of Innovative Optical Health Sciences (JIOHS), Vol. 2, No. 4, pp. 325-341, Dec. 2009.
  • Mahsa Ranji, Diego Calzolari, Ramses Agustin, Jeffrey H. Price, “Quantitative analysis of 3D Fluorescence Images,”   Asilomar Workshop on Cytometry, Oct. 2009.
  • Mahsa Ranji, Muneaki Matsubara, Bradley G. Leshnower, Robin Hinmon, Dwight L. Jaggard, and Britton Chance, Robert C. Gorman, Joseph H. Gorman III, "Quantifying Acute Myocardial Injury Using Ratiometric Fluorometry,"   IEEE Transaction on Biomedical Engineering (TBME), Vol. 56, No.6, pp. 1556-1563, May 2009.
  • Mahsa Ranji, Diego Calzolari, Natalie Prigozhina, Karen A. Wei, Mark Mercola, Jeffrey H. Price, “Automated Tracking of Migration and Diffrentation of Fluorescently Labeled Human Embryonic Stem Cells,”   Proc. SPIE Photonics west, Jan 2009.
  • M. Ranji, D. Calzolari, J.H. Price, “Quantitative analysis of deconvolution methods for fluorescence microscopy images,”   Invited, Asilomare Image Cytometry Workshop, Oct. 2008.
  • M. Ranji, M. Matsubara, B.G. Leshnower, R.Hinmon, D.L. Jaggard and B.Chance, R.C. Gorman and J. H. Gorman III, “Optical Biopsy of Apoptosis in Ischemic Myocardium with Fluorometry,”   Proc. of AHA (American Heart Association), Nov. 2007.
  • M. Ranji, M. Matsubara, M. Grosso, D.L. Jaggard and B.Chance, R.C. Gorman and J. H. Gorman III, "Fluorescence spectroscopy to assess apoptosis in myocardium,"   Proc. of SPIE, Vol. 6438, pp. 64380J1- 64380J4, Feb. 2007.
  • Mahsa Ranji, Dwight L. Jaggard, Sofia V. Apreleva, Sergei Vinogradov, and Britton Chance, "Simultaneous fluorometery and phosphorometry of Langendorff perfused rat heart: ex vivo animal studies,"   Optics Letters, Vol. 31, Issue 20, pp. 2995-2997, Oct. 2006.